Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID18399 Gsk-2126458 GSE70138 MCF10A Human 3h 1.11uM EID0024
Types Number Response transcription factors
Up-regulation 64 TSC22D3; RBPMS; FOXO3; FOXO4; HBP1; BTG1; COPS2; MXI1; DDIT3; ID2; SOX4; ZNF131; SAP30; BAZ2B; CEBPD; PAX6; HOXB7; PNRC1; TCF25; HMGB2; SIAH2; BBX; ST18; TXNIP; CITED2; FOXN3; CARHSP1; ZNF165; KDM5D; NFIL3; TCEB2; PHIP; DMTF1; ELF5; ZMYND8; KAT6B; HOXA5; SPIB; HMGN3; BRD8; ZBTB16; HOXC6; ISL1; TOB1; ZNF652; KLF6; CTBP2; PHF20; EGR1; PBX1; TBL1X; TLE1; MEIS2; TOX; CREB1; HDAC9; ZIC1; CRYM; GATA6; KLF11; ARID5B; INSM1; NR3C1; SATB1
Down-regulation 58 FOSL1; MYC; HMGA2; ARID4B; PPRC1; HOXA10; WDR77; SF1; BCOR; HES1; LEF1; ZNF557; RBL1; NUP62; LOXL2; TAL1; ETV5; BHLHE40; ADRB2; MAFB; ZEB1; BAZ1A; XBP1; KLF10; VDR; NR2F6; JUN; PRRX1; KDM5C; SP140L; ZBED2; HIC2; HHEX; CHD7; ARNTL2; BACH2; EGR2; SALL1; ELK3; POU2AF1; ZBTB18; PITX1; EGR3; BHLHE41; VPS72; SMAD7; ZFP36L1; SNAI2; TBX3; ZNF512B; SOX11; NKX3-1; FLI1; ID3; FLNA; ID1; TBX2; IKZF1