Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID18363	Azd-5438	GSE70138	MCF10A	Human	3h	1.11uM	EID0024

Response Information :

Types	Number	Response transcription factors
Up-regulation	53	PLAGL1; ZNF652; EP400; HOXA11; BATF3; TBX19; HAND1; ASCL1; EWSR1; KLF10; MYCN; FOXC1; MSX1; PGR; TOX3; STAT5A; CTNNB1; IRF5; SATB2; HOXB7; FOXJ3; HTATIP2; TBX2; HMGB3; NR4A1; HSBP1; RBBP7; ZMYND8; RUNX3; CTR9; CERS6; BATF; SP140; TOX; IRF4; ELF4; SPIB; NR2F2; FOXD1; LYL1; CBFA2T3; IRX5; MYB; ESR1; ZNF721; MAGED1; IRF7; HLTF; PAX5; HOXC6; WT1; BCL11A; KDM5D
Down-regulation	83	ADRB2; MXI1; CCNA2; NFE2L2; GTF2IRD1; ARID4B; ZNF281; HDGF; CAPN15; HBP1; NFIL3; TAF5; NFIB; SMAD4; ZNF189; LPIN2; PIAS1; FOXM1; FOXN3; CNOT6; MEIS2; SMAD1; ZNF22; HMGB1; ZHX2; ZMYND11; SOX11; ZNF112; IFI16; YAP1; ZNF32; TRIM29; TGIF1; FOXA1; BACH1; STAT1; NKX2-1; PNRC1; ZNF415; TCF4; NR1D2; KLF9; TCEA1; HNRNPD; CEBPB; KDM5B; ZNF165; ZFHX4; KLF2; ZNF232; CITED2; ZNF302; ZNF350; CENPF; HLF; MEOX1; FOXO1; ISL1; CDK8; TRIM22; ZFPM2; TLE4; ZFP36L1; IRF9; SMARCA1; TBX3; EYA1; GTF3A; ZEB1; RBL2; TFAP2C; ID4; SAP30; MNDA; ST18; WWTR1; TWIST1; ID3; PEG3; ID1; CREB1; NFATC3; IKZF1