Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID18362 Azd-5438 GSE70138 MCF10A Human 3h 3.33uM EID0024
Types Number Response transcription factors
Up-regulation 35 SREBF1; MYBL2; EDF1; ELF3; NFYC; AR; RFX5; SND1; AEBP1; NPAS2; TRIM28; BHLHE40; NR4A1; LOXL2; INSR; CREM; FOSL2; HOXB7; HOXC10; STAT1; SATB2; BCL3; PIR; ETS2; ASCL1; ESR1; BRD4; LEF1; EMX2; SATB1; MAGED1; BHLHE41; TOX3; ZBTB18; CREB1
Down-regulation 107 FHL2; FOXO3; CEBPD; TSC22D3; MYC; CCNA2; ADRB2; NFIL3; TAF1A; ZFP36L2; MED17; ARID4B; NFYB; TAF5; ABL1; ZNF12; MYBL1; ADNP; ZFP30; RNF4; ZNF93; ZNF675; NFIB; ZNF131; ARID5A; ZNF107; ZNF85; ZBTB16; ZNF571; RBPJ; ZNF22; AHR; RORA; ZNF273; ZNF43; JUN; TXNIP; ZSCAN9; DDIT3; ZNF14; RAN; MEOX1; MTF2; BACH1; SP140; FOXF2; SAP30; HOXA5; BRD8; FOXK2; PRDM1; CEBPB; CAMTA1; TSC22D1; BRWD1; RCOR1; ILF2; MED21; ZNF281; GFI1; XBP1; ZNF410; MYT1L; ZNF124; ZNF195; TRPS1; MEIS2; KDM5B; ELF5; ZNF232; JAK2; CENPF; NRBF2; ZNF165; STAT4; SPIB; FOXO1; EGR1; TCF7L1; EN1; TP63; KLF6; POU2AF1; BTG1; FLI1; ZEB2; MEIS1; ZIC1; TBX3; ZNF117; TRIM22; ID1; FOXG1; MAFB; HIC2; HDAC9; ID4; PAX5; TRIM29; ZBTB38; TGIF1; BASP1; GATA6; ID3; EGR2; SUV39H1; NFATC3