Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID18342	Canertinib	GSE70138	MCF10A	Human	3h	0.04uM	EID0024

Response Information :

Types	Number	Response transcription factors
Up-regulation	54	TCFL5; TSC22D3; ID2; RNF141; MAGED1; SMARCA2; DPF2; ARID4A; NR1H3; MEF2C; HMGB3; TXNIP; E2F8; PEG3; BAZ2A; HMGN3; POU2AF1; SIAH2; HIPK3; ZNF652; RCOR1; TAF9B; RCOR3; KAT6B; NCOA1; TRIM22; ZKSCAN1; NCOA2; CRYM; DEAF1; PBX1; PPARGC1A; RBBP4; SMAD5; ASH2L; FLI1; MKL2; PRKDC; ZNF468; SAP30; IRF7; JUP; CTR9; TLE4; PAX5; TCF4; ZNF423; LMCD1; BASP1; MAFB; PIR; TRPS1; TLE1; CITED2
Down-regulation	77	FOSL1; HMGA2; MYC; FHL2; EGR1; MAFF; KLF4; MAFG; PPRC1; JUN; JUNB; PCGF1; HOXB2; HES1; ETV4; SUPT4H1; SMAD3; MYCN; MEOX2; ZNF573; RUNX1; CBFB; SHOX2; SMAD7; RARA; NAB1; SOX9; PCGF2; BCL3; TCF7L2; BHLHE40; CEBPB; LITAF; PITX1; ZEB1; ISL1; SMARCA1; YBX1; MBD2; AHR; TRIB3; PFDN5; FOSB; TGFB1I1; BRD4; HDAC9; EYA2; ADRB2; NEUROD1; JUND; ZBED2; HOXB7; IRF6; MSX1; HEY1; CALR; MECOM; ZFP36L2; GATA6; SATB2; ELK3; HOXB6; ETS2; FOXF1; ATF3; EGR2; INSM1; ESR1; ASCL1; ID4; ID1; FOS; DACH1; EGR3; IKZF1; KDM5D; TBX2