Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID18341 Canertinib GSE70138 MCF10A Human 3h 0.12uM EID0024
Types Number Response transcription factors
Up-regulation 28 TSC22D3; ID2; ZMYM2; MXI1; MEIS2; CEBPA; ZNF268; PSIP1; RFX5; AEBP1; ESRRG; FOXN3; PHIP; BRIP1; TBL1XR1; OSR2; NFATC3; HMGN3; TOB1; HOXD1; TRIM29; PIR; PEG3; TLE1; EMX2; HOXC6; CRYM; FOS
Down-regulation 41 FOSL1; MYC; HMGA2; FHL2; HES1; EGR1; BHLHE40; ARID4B; KLF10; MAFF; MTA1; LOXL2; JUN; SOX9; EGR3; HHEX; XBP1; KLF4; FOXA2; ETS2; CALR; TOX3; AHR; HMGA1; EGR2; ADRB2; SATB1; SATB2; ELK3; FOSB; SMAD7; SOX11; HDAC9; FOXF1; ID4; ZEB2; ZFP36L1; KDM5D; BHLHE41; TBX2; IKZF1