Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID18336 Afatinib GSE70138 MCF10A Human 3h 0.04uM EID0024
Types Number Response transcription factors
Up-regulation 13 TCFL5; TSC22D3; ID2; ZMYM2; FOSL2; KAT6B; HOXC10; ZNF331; TOX; TXNIP; ZIC1; TRIM29; HOXC6
Down-regulation 39 FOSL1; MYC; HMGA2; FHL2; EGR1; NR4A1; SOX9; TOX3; BHLHE40; MEOX1; EGR4; EGR3; JARID2; CHD7; KLF10; LOXL2; TLE1; NKX2-1; BACH2; ADRB2; HDAC9; FOSB; FOXD1; ID4; ZFP36L1; SMAD7; ZBTB18; ESR1; CRYM; INSM1; MYB; TSC22D2; ASCL1; ELK3; SATB1; EGR2; KDM5D; TBX2; IKZF1