Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID18335	Afatinib	GSE70138	MCF10A	Human	3h	0.12uM	EID0024

Response Information :

Types	Number	Response transcription factors
Up-regulation	55	TSC22D3; ID2; SAP30; RARB; RFX5; HMGN3; MAGED1; ZIC1; RCOR3; CUX2; BCL11B; XRCC6; EYA1; RNF141; CBX5; ZMYND8; PROX1; ISL1; MEF2A; HOXC10; TP63; MYCN; NR1D2; RORA; LEF1; PITX2; PPARGC1A; PBX1; ZNF329; AES; HOXB7; ESRRG; EHF; NR2F2; SALL1; PIR; ZNF302; SMARCA1; HOXC6; MYT1L; TOX; RBPMS; TOB1; CREB1; HIPK3; CITED2; TRIM22; SATB1; ADRB2; KLF9; ID4; CRYM; SOX11; TLE1; MEIS2
Down-regulation	57	FOSL1; ABL1; MYC; FHL2; HMGA2; NRIP1; PPRC1; EGR1; E2F3; CHD1; ARID4B; ETV4; RNF138; ZNF593; CEBPB; BCL10; CCNE1; VDR; HES1; CNOT6; MED17; RUNX1; PRRX2; JUN; SMAD3; NR1H2; NPAS2; MAFF; RBPJ; TSC22D4; NR4A1; NRBF2; SATB2; ZNF430; NFE2L3; ELF4; SERTAD2; LOXL2; EGR3; TRIB3; FOXD1; SOX10; SOX9; FOSB; NR4A2; ZFP36L2; HIC2; FOS; SNAI2; TFAP2C; TBX3; MYRF; ATF3; ESR1; EGR2; IKZF1; TBX2