Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID18334 Afatinib GSE70138 MCF10A Human 3h 0.37uM EID0024
Types Number Response transcription factors
Up-regulation 24 VGLL4; TCFL5; TSC22D3; ID2; TADA3; HMGN3; BAZ2B; TRIM24; SMARCA2; TFDP2; BRD8; HOXD1; HIPK1; TWIST1; RBL2; NR1D2; PIR; TLE1; MAGED1; GTF3A; JUP; SATB1; PTTG1; KDM5D
Down-regulation 47 FOSL1; HMGA2; MYC; FHL2; EGR1; PPRC1; SOX9; EGR3; CTBP2; KLF10; MAFF; TAF1D; HES1; BHLHE40; IRF8; JUN; SPIB; KLF6; RBM39; TCF7L2; BAZ1A; ZBED2; FOXL2; EGR2; ADRB2; NKX3-1; TRPS1; NR2F1; FOSB; PITX1; TSC22D1; ETS2; TBX3; SALL1; NFE2L3; HIRA; ZFP36L1; PAX5; MYBL1; ID4; PBX3; CRYM; POU2AF1; SSBP2; NFATC3; IKZF1; TBX2