Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID18332	Afatinib	GSE70138	MCF10A	Human	3h	3.33uM	EID0024

Response Information :

Types	Number	Response transcription factors
Up-regulation	90	TCFL5; TSC22D3; KDM5A; HMG20A; ID2; SP110; HMGN3; HMGB3; JAK2; TXNIP; SPIB; HDAC5; PSPC1; SIAH2; E2F2; ARID5A; SOX3; SND1; MAGED1; TCF25; NR1I3; RXRA; ARRB1; E2F8; MEF2C; ZNF33B; PIR; PBXIP1; CRYM; KAT6B; AR; RBBP4; NR5A2; CTBP2; TCF4; HIPK3; IRF7; BCLAF1; SOX10; TFEC; HHEX; SUB1; KAT2B; BTG1; PPARGC1A; ZSCAN31; NR3C2; PLAGL1; NR1H4; TBL1XR1; WNT4; BRD8; FOXE1; BLM; RNF141; HLTF; CIITA; FLI1; BATF3; BASP1; TRIM22; PAX5; IRX5; OSR2; IKZF1; IRF4; TFCP2L1; NKX2-1; TP63; HLF; SSX1; IRF8; MYT1L; ZEB2; IRF9; HEY2; ARNTL; RNF14; PBX1; MYBL1; SATB1; KLF2; SHOX2; CTNNB1; JUP; ASCL1; HOXC6; TLE1; PTTG1; KDM5D
Down-regulation	64	FOSL1; MYC; FHL2; HMGA2; CAPN15; PPRC1; SOX9; MAFF; EGR1; AGO2; ZNF281; C1QBP; NCOA6; NAB1; HES1; YAP1; BRD7; NR2F1; ZNF83; CUX1; CBFB; PTRF; GTF2IRD1; KLF5; ZEB1; NR4A2; ZKSCAN7; CALR; CHD7; ZNF573; JUN; HOXB2; ZNF329; DACH1; EGR2; BHLHE40; DLX2; CD3D; ST18; TBL1X; LEF1; HMGA1; MAF; ADRB2; RBPJ; SNAI2; SATB2; CRY1; TGFB1; ID1; TGIF1; TGFB1I1; SMAD7; FOXG1; TOX; EGR3; TRIB3; FOXC1; TRIM29; TOX3; ELK3; PPARG; ZNF586; TBX2