Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID18330 Celastrol GSE70138 MCF10A Human 3h 0.04uM EID0024
Types Number Response transcription factors
Up-regulation 30 SP110; KLF7; PAWR; RFX5; KLF4; RXRA; TSC22D1; BACH1; BCL11A; TXNIP; HTATIP2; POU2AF1; IRF6; VDR; FOS; KLF6; IRF8; NFATC3; MAFB; MED1; ZNF117; ETS2; CREB1; MYCL; FLI1; ZEB2; PAX5; SATB1; ARNT2; KDM5D
Down-regulation 32 HMG20B; NRIP1; ZNF133; HMGB2; LPIN2; BRD3; HOXC10; YBX1; TLE2; NKX2-2; HLF; RORA; NR2F1; RBPMS; CITED1; BRD2; MYT1L; SMAD7; SMARCA1; WWTR1; HOXC6; NKX3-1; GTF3A; PEG3; BHLHE40; RBBP8; ZBTB16; HLTF; MEIS1; ELK3; ATF3; IKZF1