Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID18326	Celastrol	GSE70138	MCF10A	Human	3h	3.33uM	EID0024

Response Information :

Types	Number	Response transcription factors
Up-regulation	74	NCOA3; ID2; DDIT3; GABPB1; FOXO3; ATF4; AFF4; XBP1; ZNF473; TULP4; NRIP1; EP300; KDM5A; ADNP; NR4A3; ZNF165; CHD1; OSR2; ADNP2; AGO2; ABL1; ARID4B; RFX7; TRIM24; CAMTA1; JUNB; LEF1; FOS; MAFF; SMAD5; PIAS2; CRY1; TEAD1; HSF2; MSX1; CERS6; NR4A1; HOXC6; PGR; FOXJ3; CEBPA; ZSCAN31; TBL1X; WWP1; FOSL2; GRHL2; JARID2; PIR; NR4A2; NPAS2; ELF4; CITED1; TSC22D2; ATF3; DNMT3B; MYCN; RUNX3; ZIC1; FOXA1; BRD2; FOXD1; KLF10; TRIB3; TOX; PEG3; RBPMS; TSC22D1; FOXF2; FOXG1; NR2F2; TGIF1; BASP1; AFF1; ZBTB38
Down-regulation	65	NFKBIA; ATF5; ADRB2; SMAD3; MLX; HDAC3; ZNF24; APEX1; IFI16; NUP62; CENPB; MXI1; SP100; ZMIZ2; TCFL5; ZNF593; TFAP2A; SP140L; VDR; KAT2A; EGR1; CBX3; FUBP1; BAZ1A; ASH2L; MKL2; ARID1A; TCEA1; ERBB4; ZBED2; ARNTL2; NFE2L3; HMGB3; KAT2B; ZNF423; ZNF430; ZNF512B; MNDA; ZNF264; CHD7; ZNF160; VPS72; TP63; NKX2-1; ZEB2; NR2F1; MYBL1; ID4; SATB2; MAF; ZNF91; SATB1; GTF3A; SNAI2; TRIM22; EGR2; TCF4; MECOM; PBX3; ZFP36L1; BHLHE41; SUV39H1; MEF2C; IKZF1; E2F2