Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID18325 Celastrol GSE70138 MCF10A Human 3h 10uM EID0024
Types Number Response transcription factors
Up-regulation 35 LEF1; SOHLH2; FOXG1; EYA1; PRRX1; NKX3-1; FOS; NKX2-2; CARM1; GATAD2A; TOX; FOXA2; JUNB; HEY1; TCF7; TCF7L1; TGFB1I1; KLF4; TCF7L2; ISL1; ASCL1; HMGN3; DLX5; SIX1; AEBP1; BCL6; MAFB; ST18; MSX1; PITX1; HOXD1; TGFB1; PAX5; MEIS2; ID1
Down-regulation 20 CHD9; ZMYM2; MED13; FUBP1; BMI1; RYBP; HDAC9; HLTF; SATB1; AFF1; ID4; MYRF; HOXB2; BHLHE41; MECOM; ATF3; KDM5D; TBX2; NFATC3; IKZF1