Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID18314 Ql-x-138 GSE70138 MCF10A Human 3h 3.33uM EID0024
Types Number Response transcription factors
Up-regulation 127 HOXA10; TXNIP; TSC22D3; NR3C1; LHX6; STAT4; RUNX1; SIX1; LEF1; FOXC1; MXD4; ID4; TBX21; CDYL; PKNOX1; CHD7; NR1D2; RERE; HEY2; ZNF14; NFE2; ID3; MSX1; HABP4; CIR1; SIM2; TCF7L1; JUN; E2F5; ELF3; HDAC4; RXRA; ZNF493; ZBTB43; SERTAD2; AGO2; HOXC10; BRD3; MXD1; RREB1; EZH1; DACH1; IRF1; MNAT1; SP100; ARID4A; MEOX2; MECOM; ZNF22; HOXB2; ZNF711; TCF7; HEY1; KLF1; RFXANK; DNAJC2; ELK4; CUX1; CNOT6; NR2F2; ZKSCAN1; SP140L; ZEB1; SMAD3; OLIG2; DLX2; KAT2B; ASCL1; ID1; KAT6B; SSX1; GATAD2A; CBFA2T3; WNT4; TFCP2L1; TBX2; ZIC1; KLF2; MAGED1; ZFP36L2; ZBTB38; SIM1; KLF5; SALL1; EYA1; HOXB7; POU4F1; IRF9; BHLHE41; NCOA4; PHIP; BASP1; IKZF1; EN1; HOXD11; ZBTB20; ELF5; KLF13; ADRB2; FOXD1; TAL1; ZNF721; NFATC3; SOX10; CRYM; CREB3L2; ZNF160; FOXG1; FOSB; INSM1; HLTF; TRIP6; NR4A2; HOXB6; KLF9; NR2F1; ZSCAN18; WWTR1; SATB1; TCF4; FOXF1; MYBL1; MAF; FOS; KDM5D; DLX5; CREB1
Down-regulation 90 SREBF1; TAF1D; PSPC1; PPRC1; TBX3; ZNF32; GLI3; MAFB; RNF138; BNC2; JUP; HMGXB4; XRCC6; C1QBP; CBX3; HMGA1; ZNF532; MED17; CENPB; AATF; MEIS2; ZNF232; SAFB2; CNOT2; ZBTB18; BTAF1; SAP30; ZNF281; CALR; MXI1; THAP7; PA2G4; ZBED1; TRIM28; HDGF; ZNF24; ZBTB16; PRDM10; ZNF580; ZNF217; KLF11; AR; EHMT2; RNF6; ENO1; TOX3; BAZ1A; CARM1; LDB1; NR2C1; YWHAB; GATA6; MITF; MYRF; ZNF467; ZNF267; TRIB3; HMBOX1; REL; LIN28A; TCF7L2; CERS4; LOXL2; SPIB; E2F8; RORA; ZFP36L1; FOSL2; ELF1; HHEX; IRF4; RUNX3; MAFF; WT1; ERBB4; ZNF589; TCEA2; IRF7; NFE2L3; ST18; BHLHE40; INSR; GTF3A; PITX1; SMAD1; EGR3; TGFB1I1; CITED2; ZEB2; ZNF586