Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID18271 Saracatinib GSE70138 MCF10A Human 3h 10uM EID0024
Types Number Response transcription factors
Up-regulation 47 TSC22D3; NR1H2; ESRRG; NFIL3; MEIS1; FOXO4; SMARCE1; AIP; HES1; ADRB2; CUX1; ZIC1; BRD8; KAT2B; NR4A2; BBX; TBX2; KDM5D; NFIB; TRIM29; ZFHX3; OSR2; LMCD1; RBPMS; NR1D2; EYA2; TCF21; NR2F1; CREB3L2; SMARCA2; ZNF331; BHLHE40; HOXB7; TOX; TBL1XR1; PITX1; TLE1; TSC22D1; SATB1; ATF3; FOSB; FOXF1; FOS; BHLHE41; NR2F2; PIR; POU2AF1
Down-regulation 66 FOSL1; MYC; FHL2; HMGA2; HHEX; ZFX; EGR1; BCL10; GATAD2A; CREBL2; LOXL2; ID2; ZNF91; MAFF; FOXG1; TCF7L2; CBFB; BAZ1A; ZNF93; PRRX1; DLX2; EGR4; MSX1; NKX2-1; MKL2; NR0B1; ESR1; NR1I2; IRF8; ZNF117; CEBPB; KLF10; ASCL1; SOX9; MAFB; NFE2; TSC22D2; ETS2; BCL11B; MYB; MNDA; EGR3; PITX2; HIRA; FOXO1; ELK3; NFE2L3; ZNF267; INSM1; TCF4; TOX3; LEF1; ID4; MYBL1; ZEB1; SOX11; TBX3; TFAP2C; ID1; DACH1; DLX5; GATA3; MEF2C; EGR2; E2F2; IKZF1