Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID18264 Fostamatinib GSE70138 MCF10A Human 3h 0.04uM EID0024
Types Number Response transcription factors
Up-regulation 49 HOXA10; TCF12; ZMIZ2; PHOX2A; SUV39H1; FOXG1; TCF7; REPIN1; ZNF215; CREM; BAZ2B; PRDM1; POLR2A; NAB1; BRCA1; HEY1; AHR; NFAT5; SSX1; PHOX2B; LYL1; CCNE1; TBX2; EYA1; ZNF160; SATB2; XBP1; ZNF721; KLF2; BBX; STAT1; ZBTB18; SOX10; NFE2; SATB1; SMARCA2; JUND; POU4F1; PRRX1; BHLHE40; FOXD1; MSX1; MEOX2; HOXD1; HDAC9; AFF1; JUP; ATF3; MYB
Down-regulation 68 ZNF227; FOXL2; CARM1; DBP; PSPC1; PBX1; RCOR1; OSR2; MEIS1; IRF8; FUBP1; CTBP2; ZNF232; LOXL2; CBX6; KMT5A; L3MBTL1; CREB3L1; ZNF266; RXRA; BRWD1; RNF138; PAXBP1; SOX11; REL; FLNA; ZNF273; BAZ1A; RBM39; ZSCAN31; PEG3; NFIB; WT1; YBX3; PBX3; CHD7; BCL6; EMX2; PAX5; PITX1; ZFPM2; ZFP36L1; RUNX3; TFEC; TLE4; ZNF83; BASP1; WWTR1; HOXB6; MYT1L; SMAD1; TRPS1; NKX3-1; ERBB4; NR2F1; ZNF91; ID1; SOX9; TOX3; MAF; MYRF; ESR1; GATA6; CITED2; CREB1; IKZF1; KDM5D; E2F2