Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID18260 Fostamatinib GSE70138 MCF10A Human 3h 3.33uM EID0024
Types Number Response transcription factors
Up-regulation 45 YBX2; HDAC6; MTA2; TBL1XR1; ZBTB16; NKX2-2; MTF2; ZMIZ1; E2F2; SPI1; RSF1; NR1H3; CITED1; RAN; ZMYND8; BBX; ZNF652; EGR1; ESRRG; TFDP2; AES; CTNNB1; MDM4; ZNF721; ZIC1; GTF2I; TAF9B; PAX6; SPIB; LOXL2; ZBTB20; FOXE1; ZNF43; NR0B1; TP63; SOX9; BTG1; NEUROD1; HHEX; KDM5D; PTTG1; BASP1; INSM1; ELK3; SOX11
Down-regulation 43 TAF11; RYBP; ZNF423; ADRB2; SMAD7; RARA; MAFB; NCOA6; CBX3; BNC2; CD3D; RXRA; FOSL2; PEG3; MITF; MEIS2; MTDH; NR2F1; CITED2; HOXC10; ZEB2; CTR9; PIR; HLF; TLE4; SCAND1; RUNX3; ETS2; POU2AF1; TCF21; SNAI2; KLF2; ID1; IRF4; ID4; EMX2; ESR1; CREB1; NFATC3; EGR2; IKZF1; MEF2C; TBX2