Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID18259 Fostamatinib GSE70138 MCF10A Human 3h 10uM EID0024
Types Number Response transcription factors
Up-regulation 60 TSC22D3; EGR1; MZF1; ADNP2; PLAG1; ZFHX3; HOXB7; ZMIZ1; ZNF652; CDX1; FOSB; MED14; BTG1; NR4A1; HOXA5; SMAD4; GATA3; SOX13; FOS; ATN1; CHD9; BRD8; CREB3L1; SMARCC2; JUNB; TOX; TXNIP; SIX2; TRIM29; PNRC1; PHIP; TWIST1; KLF4; ELF4; TRPS1; ZFHX4; ZNF721; VDR; AES; SATB2; TOB1; AEBP1; MECOM; PITX1; MEOX2; NR4A2; TLE4; INSM1; GATA6; ATF3; SOX17; MEIS1; ZFPM2; CREB1; INSR; ZIC1; ZBTB20; PBX3; JUP; ARID5B
Down-regulation 33 MYC; FOSL1; ADRB2; HMGA2; TRIM16; NR1H3; TAF9; BAZ1A; NKX3-1; SOX9; STAT3; NR2F1; ZNF267; MAFB; HLF; FOXE1; ELK3; BCL11B; DLX2; NKX2-1; SMARCA1; TOX3; CRYM; BMI1; MYBL1; FOXC1; ID4; HDAC9; ZNF91; TRIM22; TFEC; SATB1; IKZF1