Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID18253 Gsk-1059615 GSE70138 MCF10A Human 3h 10uM EID0024
Types Number Response transcription factors
Up-regulation 70 TSC22D3; ID2; ZNF589; FOXO3; FOXN3; CEBPD; EZH1; HBP1; HDAC5; MXI1; RAD21; TCF25; ZMYND8; RORA; PNRC1; ZIC3; ZNF500; GATA3; ZFHX3; ZNF688; SALL2; TRPS1; ZBTB16; LIN28A; PHIP; HOXA5; ZNF580; SMAD6; SOX4; CBX7; CAMTA1; MAF; CNBP; ELF5; PHF20; ZNF331; EN1; DLX5; TXNIP; TRIM22; ZNF532; ZNF217; LMCD1; ZNF467; NANOG; SOX2; ERBB4; MAFB; ARID5B; ZHX2; HEY2; HMGN3; NFATC4; ZNF512B; DLX2; ARNT2; RBPMS; ZSCAN18; INSM1; FOXO1; KDM5D; CITED2; TWIST1; ESR1; TCF4; TFAP2C; HEY1; BCL11A; TLE1; POU2AF1
Down-regulation 60 FOSL1; MYC; HMGA2; FHL2; TBP; PPRC1; ADRB2; CHD1; EED; HES1; HOXA10; KLF10; ELF3; LEF1; ETS1; BHLHE40; CHD7; PITX1; NUP62; NR4A1; TRIM16; NR2F6; EGR1; NKX3-1; PLAGL2; MAFF; TFAM; ALX1; SUB1; JUNB; XBP1; KLF4; ELK3; MED6; EGR3; RNF6; HSF2; ETV5; FOXC1; BATF3; NFE2; VEZF1; CBFB; BCL3; NR4A2; BAZ1A; ZBED2; MNAT1; ZNF267; MED1; EGR2; WWTR1; ZBTB38; SOX9; DACH1; ZFP36L1; CREB1; ZEB2; ID1; IKZF1