Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID18212 Mitoxantrone GSE70138 MCF10A Human 3h 0.04uM EID0023
Types Number Response transcription factors
Up-regulation 102 SP140L; SOX4; TCEA2; MZF1; IRF5; NCOA1; NR1H2; NFE2; MED13; TRIM22; GLI2; ZKSCAN4; TAF1C; BAZ2B; CREB1; ZNF274; ZNF467; ZNF135; ZNF140; MDM2; KAT2B; HIVEP1; AHR; IRF7; ZNF124; ZNF562; ZNF175; KLF11; PEG3; ZNF136; ZNF665; ZNF669; BNC2; MYCL; ZNF133; SSBP3; PKNOX2; CDIP1; SCAI; ZNF654; ZNF91; CITED2; JUND; THRA; ZNF500; ZNF667; MYBL1; ZNF304; ZNF85; PNRC1; KLF4; ZNF264; TCF21; JAK2; TGIF1; REL; ZEB1; ZNF43; TLE4; CUX1; CALCOCO1; ZFP36L1; CIITA; ZNF652; ZNF232; ZNF350; ZNF12; CBFA2T3; SOHLH2; ZBTB20; ID4; ELF5; ARID5B; WNT4; NFE2L3; TGFB1; ZNF331; ZNF430; IRF9; SSBP2; AR; ZNF329; HLX; ERBB4; ZFPM2; ZSCAN18; TFAP2A; CAMTA1; FOXF2; HIRA; PLAGL1; MXI1; IRF8; MEIS2; TOX3; DLX5; ZNF586; SATB2; NFATC4; ST18; ZNF423; LEF1
Down-regulation 27 ATF6; MYC; BRCA1; BRD8; STAT3; NFATC1; HOXC6; RNF4; NFIL3; SMAD2; SMARCE1; MTDH; RHOA; CENPF; PTTG1; HMGN3; SREBF1; NRIP1; CHD7; RBBP4; NFIB; SOX9; NUP62; EGR3; CBFB; HLTF; PUF60