Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID18184 Torin-1 GSE70138 MCF10A Human 3h 0.04uM EID0023
Types Number Response transcription factors
Up-regulation 188 KDM5B; PMS1; BARX1; ATF2; GATA2; TGIF2; ARNT; FLI1; CEBPD; KLF9; KLF7; PEG3; PROX1; TTF2; ZNF532; SETDB1; MEF2D; HIC1; TBX21; ERBB4; TRPS1; PRDM2; YBX2; CDIP1; HOXA6; SPI1; HLX; SIX6; PPARD; PNRC1; ZIM2; EN1; PITX3; FOXI1; NFIC; PRDM14; CBX2; SIX2; ZNF74; ARID3B; CEBPZ; HIPK3; ONECUT1; NFATC4; ALX3; EPAS1; SUPT3H; ZNF665; HIPK2; ZBED2; ZNF415; KLF11; SALL2; ZNF623; TBX1; SOX18; SOX21; ZIC1; HBP1; NFKB2; KLF3; NFIX; SRCAP; BRWD1; ZNF141; HHEX; HIF3A; SOX5; HDAC5; PIAS4; ZKSCAN8; TCF7L1; PLAG1; CBFA2T2; ZNF589; CREB1; ZNF43; PEX14; PKNOX2; GATA1; THRB; TFAP2A; FOXH1; GTF2I; SSBP2; BCL11A; ZFP2; VPS72; ZFPM2; ZNF253; ZNF573; TWIST1; PAWR; CARF; MBD4; PBX3; BRIP1; FOXA2; MECP2; HDAC9; ETS1; HINFP; SOHLH2; TCF4; RARG; SIX1; SRY; PBXIP1; PAX5; HOXB5; TP73; ZNF217; POU5F1B; GLI2; INSR; CIITA; TOX; FEZF2; ZEB1; PCGF3; ZIC3; HOXD1; CREM; ZNF235; ARID5B; MYCN; KLF13; MEIS1; NR1H2; TULP3; WT1; PRDM12; ZNF85; LOXL2; ZNF154; ZNF423; ZNF232; ESRRG; CUX2; NFE2; HMBOX1; ZNF239; ZNF345; AEBP1; HEY1; BNC2; MYBL1; ZNF331; SATB1; TCEA2; ZNF83; NANOG; ZNF91; NKX2-2; ZHX2; MEIS2; SMARCA1; NR5A2; ARNT2; SPDEF; ZNF117; SOX11; ZSCAN18; NR0B1; LIN28A; KAT2B; NEUROD1; NFATC3; FOXG1; MECOM; ESR1; HOXB2; TCF21; PBX1; NFE2L3; HIC2; REL; PAX6; KLF4; ZNF264; SOX17; NR4A2; CBFA2T3; ZBTB20; NR2F6; IRF9; SNAI2; TRIB3
Down-regulation 59 SUV39H1; TCERG1; NCOA4; GABPB1; RBM14; TRIM28; COPS5; YWHAB; NR2F2; FOSL1; USF2; SFPQ; TBP; MTF2; SUB1; JUNB; PSIP1; TRIM32; SOX9; UBE2I; HOXC6; EZH2; IKBKAP; RNF4; YBX1; SPEN; ERBB2; HSF2; MBD2; UBP1; BRD2; MAGED1; MTDH; FOXJ3; RBBP7; AFF1; MED1; RNF6; FOXC1; ZBTB18; ELF1; SMARCA2; ID2; RBBP4; ARID1A; CBFB; HMGN3; NKX3-1; PTTG1; EGR3; TRIP6; TRIM16; PIR; MSX1; BASP1; BMI1; PUF60; EED; KDM5D