Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID18171 Gsk-2126458 GSE70138 MCF10A Human 3h 0.12uM EID0023
Types Number Response transcription factors
Up-regulation 48 E2F2; TSC22D3; FOXO3; NR3C1; NFIL3; PPARGC1A; MAGED1; SOX4; TFCP2L1; CDK7; ADRB2; IRX5; SMAD2; BTG1; HMGB3; RNF14; NFKBIA; ARNTL; FOXN3; HOXC6; BRD8; ID3; ID2; NCOA4; RBBP4; ZBTB16; RBPMS; ZBTB38; NR1D2; ZBTB1; KDM5D; SAP30; MXI1; HBP1; ZIC1; HOXA5; TLE1; HMGB2; BASP1; KLF9; HMGN3; KLF2; HLTF; TXNIP; BMI1; CREB1; NR2F2; PUF60
Down-regulation 83 FOSL1; MYC; PPRC1; EGR2; LOXL2; SRF; HES1; EGR3; ETV5; BHLHE41; HMGA2; EGR1; ZNF710; BCL10; NR4A1; MAFF; TFAP2C; TGFB1I1; PKNOX2; JUN; ZNF516; NAB2; ESR1; ZNF593; ZNF580; NR4A2; LZTS1; HHEX; SALL1; ZFP36L1; EGR4; ASH2L; HDAC9; KDM5C; TSC22D2; HEY2; VDR; CALR; NR0B1; CCNE1; ZEB2; NANOG; SOX5; TRIM24; MED14; MYRF; WT1; LIN28A; NFE2L3; ID4; IRF4; BCL3; ZBED2; FOXD1; SOX17; SOX13; HOXB2; NR4A3; ZNF512B; ARNT2; HIC2; TGFB1; TWIST1; ZNF331; NFATC4; SHOX2; SOX2; ZHX2; ELF5; PEG3; MECOM; MNDA; MYCL; MEIS2; DLX5; EHF; LEF1; ID1; EMX2; ZNF423; SATB1; SNAI2; ZFPM2