Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID18168	Gsk-2126458	GSE70138	MCF10A	Human	3h	3.33uM	EID0023

Response Information :

Types	Number	Response transcription factors
Up-regulation	92	TSC22D3; TFCP2L1; BTG1; TXNIP; SMARCA2; IRF5; NFKBIA; NR3C1; HIPK3; PAX8; HMGB3; ING3; SOX2; PPARGC1A; HOXC6; FLI1; ZNF226; SP100; MBD2; BCLAF1; HBP1; UBE2B; TBL1XR1; ZNF467; MAF; TFDP2; SMARCE1; BRD8; TRIM29; FOXO3; BRD2; KLF6; HDAC5; TADA3; NFIL3; YBX1; HMGB2; SUMO1; RNF10; YWHAB; PIR; HOXB7; CTR9; LITAF; HOXC4; NR1D2; HSBP1; KLF5; TAF10; TGIF1; NPM1; PEG3; MEIS1; RNF141; HOXC10; TRPS1; NRIP1; ATF4; ENO1; SOX4; PLAGL1; HMGN3; BASP1; HOXA5; MYCN; ID2; RBPMS; TRIM22; ZBTB1; SAP30; MAFB; AFF1; PNRC1; SMAD2; KLF4; TOB1; ZKSCAN1; HTATIP2; PHIP; NR2F2; NR2F1; TFEC; EMX2; HOXB6; HLTF; CREB3L2; TLE4; KLF11; MYCL; ASCL1; CREB1; KDM5D
Down-regulation	56	FOSL1; MYC; HMGA2; SOX9; PPRC1; MYBL1; TAF1A; JUNB; SRF; WDR77; EGR1; EGR3; ZNF692; HES1; ZEB1; BCL10; HOXA10; UBE2I; ZNF263; NR4A1; TAF9; BCL11B; WHSC1; TLE2; ADRB2; SFMBT1; ZNF189; RUNX1; NAB2; ESR1; LOXL2; EGR2; PCGF3; ZBTB18; TGFB1I1; LEF1; EGR4; ZFP36L2; NFIC; EYA2; HOXB13; CEBPZ; BHLHE40; NEUROD1; TWIST1; HIC2; MEIS2; TGFB1; FOXF2; NR4A2; ZNF117; ELK3; GATA6; SATB1; TRIB3; TBX2