Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID18167	Gsk-2126458	GSE70138	MCF10A	Human	3h	10uM	EID0023

Response Information :

Types	Number	Response transcription factors
Up-regulation	91	TSC22D3; NR3C1; PSPC1; NFKBIA; NFE2L1; SOX4; MAZ; BRD3; BRD8; BTG1; HOXC6; BCLAF1; KLF6; SMAD4; RCOR3; IRF7; SIRT7; UBE2B; TBL1XR1; CTR9; KDM5B; ZNF226; ZMIZ1; STAT5B; CNOT6; ATF4; KAT7; EZH1; RNF14; ARNTL; CITED2; ZBTB1; HBP1; NFIL3; HTATIP2; ARID4B; PNRC1; ZMYM2; DDX5; FOXO3; PBXIP1; MED24; DNMT3B; NCOA1; ATF7IP; COPS5; NR1D2; AFF1; TGIF1; PIR; CTBP2; USF2; MED1; MED13; MYB; TSC22D1; PSMC3IP; ENO1; AEBP1; MEF2A; MXI1; ZBTB18; HDAC5; KLF9; BAZ1A; ID2; IRX5; TLE1; TFCP2; ZMIZ2; PRKDC; ZNF266; RBBP4; NCOA2; HOXC10; ZKSCAN1; ZNF721; TOB1; TRIM22; CENPF; FOSB; ZBTB16; RBPMS; HLTF; ASCL1; TRPS1; ID4; HMG20B; TCF4; BMI1; CREB1
Down-regulation	162	FOSL1; MYC; HMGA2; ZFP36L1; ETV5; EGR2; EBF2; HES1; SOX11; SRF; EGR3; MEOX1; ZNF512B; ZNF14; NFAT5; ZNF593; POU4F2; PKNOX2; PFDN5; MYEF2; NEUROD1; SP140; CREB5; E2F3; ZBED2; ZNF287; ZNF432; EGR1; CREG1; ZNF334; PROX1; TCEB2; MECP2; TCF7L1; BACH2; ZNF124; ZNF675; PLAGL2; HIC1; LOXL2; LHX1; ZSCAN9; ELK3; SIX6; ZNF749; HOXD1; ZNF32; ZNF180; POU1F1; ADRB2; ZEB1; ZNF835; HOXD11; THAP10; HOXD3; IKZF3; SOX5; ZNF536; TOX; TGIF2; TFAP2A; ZNF415; BNC1; ZNF354A; ZNF141; MECOM; NHLH2; AFF2; ISL1; ZNF22; ZNF43; PAX4; ZKSCAN8; VPS72; ZNF253; ZFP69B; IFI16; FOXF2; TAL1; TP63; ZNF695; CHD2; TGFB1I1; HDAC9; TP73; ZNF257; SUB1; CREB3L1; MYT1; SOX18; RBFOX2; HHEX; ZEB2; ZNF112; ZNF136; CREM; HOXA10; CCNE1; ZNF239; EYA1; ZNF85; HOXB6; SALL1; SOX3; ZNF268; PRRX1; SALL2; BCL6; ZFHX4; HIC2; ZNF667; LHX3; ETS1; HEY1; ST18; FOXF1; HOXA5; BRWD1; ZNF232; ZFPM2; ZNF93; EHF; MYCN; BRD4; MEIS2; BNC2; ZNF248; PEG3; NFATC4; ZNF345; NR4A3; ZNF423; ZFP36L2; GTF3A; HOXB2; CEBPZ; SHOX2; MYRF; MEIS1; LEF1; ZNF91; ARNT2; KLF4; TCF21; TRIB3; KAT2B; WT1; KLF13; IRF9; DACH1; ESR1; ZIC1; INSM1; NKX2-1; PITX1; SOX17; EMX2; NFATC3; ZNF264; ZNF117; SNAI2; ZNF586