Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID18153 Azd-7762 GSE70138 MCF10A Human 3h 0.12uM EID0023
Types Number Response transcription factors
Up-regulation 36 RELB; HIPK3; TAF10; HOXC6; MAX; PRKDC; TADA3; TRAK1; NFIL3; YWHAB; HOXC4; BLM; BCL3; EDF1; HOXC10; PTTG1; RBBP4; TSC22D2; PURA; JARID2; SATB1; NPM1; HDAC1; RUVBL2; NR2F2; PIR; CTNNB1; PITX1; ZBTB38; KLF2; FLNA; KLF9; HOXA5; AFF1; BMI1; ZIC1
Down-regulation 86 SUZ12; HEY1; FOXA2; KLF1; ARNT2; KLF13; HOXD1; DLX5; CCNE1; FOXF2; NCOA2; BRD7; TAL1; GATA1; SERTAD2; NFE2; ELF4; PAX5; MNDA; RBFOX2; TGFB1I1; LHX3; IL16; EZH1; ZNF217; TCF12; ST18; MITF; ZEB1; ZFP36L2; TOX; SMAD7; PRDM14; JUN; ATOH1; ESR1; ERBB4; MECOM; HIC2; NFATC4; CITED2; STAT4; ZNF423; VPS72; CAMTA1; NKX2-1; ZHX2; SALL2; CREB3L2; ZFPM2; ZNF415; TCEA2; TCF7L2; HLF; HDAC9; ARID5B; FOXF1; MYRF; BNC2; CRYM; ZNF512B; LIN28A; ID4; SOX17; MEIS2; POU2AF1; TOX3; KAT2B; JUP; TFAP2C; ZNF117; CBFA2T3; TBX2; BCL11A; INSM1; SOX2; TCF21; HOXB2; ATF3; ZNF264; WT1; NFATC3; PEG3; SNAI2; ZNF586; TRIB3