Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID18133 Azd-5438 GSE70138 MCF10A Human 3h 3.33uM EID0023
Types Number Response transcription factors
Up-regulation 34 BHLHE40; ELF3; IRF5; AIP; TAF10; FOSL1; ZMYND8; HMGA1; SMARCA4; SREBF1; TRIP6; HTATIP2; KDM5D; BATF3; EDF1; RUNX1; HLTF; LMCD1; HDAC1; CTR9; PEG3; MED1; HSBP1; ELK3; JUND; SMAD2; FOXC1; ASCL1; NR2F2; HOXD1; SATB2; MSX1; PIR; CREB1
Down-regulation 121 ADRB2; CEBPD; NFIL3; BTG1; CCNA2; TAF5; HOXA1; TSC22D3; ZBTB18; ADNP2; RNF111; CHD1; ZNF184; MITF; CITED2; BCL10; TLE4; CHD8; MYC; PNRC1; FHL2; NR3C1; NPAT; BACH1; BCOR; ZNF292; TXNIP; CTCF; ZNF263; TBX3; CTBP2; SIM2; UBE2I; ZSCAN16; TRIM27; ZNF202; ZNF107; FOXO1; EZH2; ZFP36L2; ARID4B; FOXF1; ZKSCAN7; TGIF1; ZNF200; POLR3C; MAFB; TOPORS; GLI3; ATF7IP; ZSCAN31; VEZF1; ZNF45; ZBTB16; SMAD5; MYBL1; TFCP2; BNC2; ZNF165; TOB1; TCF4; ETS2; BCL11B; FOXA1; CEBPB; ZNF571; ZNF302; SMAD3; SPIB; ZNF573; FOXG1; HBP1; HIC2; TP63; HOXA10; HIVEP1; ZNF266; KLF5; MAF; MED17; ZNF500; SOX4; ZNF248; PCGF3; CD3D; SMAD1; ZFP36L1; MNDA; TLE1; MYCL; KLF6; TRIM29; GATA6; TFAP2A; TOX3; HOXB6; JUN; SNAI2; PURA; AR; ARNT2; ZNF217; MYB; FOXF2; TWIST1; EGR3; HOXA5; TSC22D1; TRPS1; KLF11; ZEB1; ZNF117; PBX1; KLF4; POU2AF1; MEIS2; DACH1; INSM1; ZFPM2; NFATC3; BASP1