Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID18111	Canertinib	GSE70138	MCF10A	Human	3h	0.37uM	EID0023

Response Information :

Types	Number	Response transcription factors
Up-regulation	63	NR3C1; PPARG; TSC22D3; TRIM29; MECOM; FOXO4; ID3; NUP62; RXRA; MKL2; ID1; HDAC5; HEY1; PKNOX2; HBP1; ATF3; YEATS4; PITX2; MED12; FOXF2; SSX1; TLE4; CREM; ZMYND8; CITED1; NCOA2; SOX13; RBPMS; HMBOX1; NR1H2; ZNF423; CALCOCO1; FOXG1; SNAI2; SOHLH2; HLX; TULP3; PNRC1; TCF4; PLAGL1; ASCL1; TSC22D1; HTATIP2; ZIC1; NR1D2; VGLL1; HOXD1; CUX2; ARID5B; TWIST1; ZNF589; MEIS2; PIR; BASP1; NR5A2; PBX1; VPS72; ST18; ZNF331; NFATC4; KLF4; INSM1; LEF1
Down-regulation	47	FOSL1; MYC; HMGA2; FHL2; PPRC1; TAF1D; EGR3; HES1; CHD1; ZNF281; KLF10; SFPQ; TSC22D2; CCDC59; SF1; SERTAD2; STAT6; IRX5; SOX9; BAZ1A; BCLAF1; ZFP36L1; JUNB; RNF138; ADRB2; EGR1; EGR4; DNAJC2; CCNC; ENO1; SIAH2; ZBTB1; HNRNPD; WWTR1; NRIP1; ELF1; HDAC1; MYB; SPEN; ELK3; CTNNB1; ESR1; NR4A2; HOXC6; EGR2; EED; NR2F6