Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID18103 Afatinib GSE70138 MCF10A Human 3h 3.33uM EID0023
Types Number Response transcription factors
Up-regulation 28 SUV39H1; TSC22D3; PQBP1; DPF2; TAF9B; RBPMS; NCOA4; JUP; YEATS4; TRIM29; TOX; JARID2; SCAND1; MITF; PEG3; SMAD2; HTATIP2; PBX1; MEIS2; PITX1; VGLL1; PIR; TRIM16; MECOM; CREB1; MAFB; HOXA5; NR2F6
Down-regulation 37 FOSL1; MYC; HMGA2; SOX9; FHL2; EGR3; EGR1; MYBL1; UBE2I; CTBP2; EGR2; JUNB; BTG1; ZFP36L2; HEY1; SMAD3; NR4A1; NRIP1; ADRB2; FOXD1; HOXA10; BACH2; ZNF83; ZNF430; ZNF248; DLX2; ZNF85; CTNNB1; CHD7; NKX2-1; LEF1; ZBTB16; NFE2L3; POU2AF1; TOX3; ASCL1; ID1