Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID18079 Pf-562271 GSE70138 MCF10A Human 3h 3.33uM EID0023
Types Number Response transcription factors
Up-regulation 78 EGR2; SRF; SOX11; NFATC3; PITX2; PAWR; CLOCK; ZFPM2; GATA6; ZNF22; RBFOX2; SOX9; ID4; DACH1; FOSB; NKX2-2; CUX2; OLIG2; NRBF2; ATF3; ZNF551; CREM; HEY1; KLF10; ASCL1; ID2; MYCN; THAP10; ZNF274; ZNF423; TOX; MYBL1; PKNOX2; MED14; ERG; NR1H4; INSR; EGR1; BRWD1; FOXG1; TAL1; EN1; KLF13; REL; ZNF711; IRF6; SOHLH2; TRIM22; WWTR1; NEUROD1; HLX; ZBTB20; WNT4; ZBED2; TCF21; CUX1; HDAC9; CBFA2T3; IRF8; PLAGL1; NR4A3; MAFB; ERBB4; FOXJ3; ISL1; ZSCAN18; SALL2; ZNF589; PEG3; ST18; IRF9; AEBP1; HIC2; ID1; INSM1; TCF4; MEIS2; NR2F6
Down-regulation 28 MYC; HMGA2; CENPF; HOXB7; SMAD3; CCNA2; SREBF1; ZMYND8; BRD8; ESR1; ADRB2; SAFB2; PHF20; KMT2A; RNF6; AFF1; YWHAB; HOXB6; NUP62; MED6; STAT3; FOXD1; NPM1; TLE1; ZBTB38; MAGED1; HOXC6; HLTF