Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID18066 Palbociclib GSE70138 MCF10A Human 3h 10uM EID0023
Types Number Response transcription factors
Up-regulation 12 HOXA10; KAT6B; HOXB7; ZBTB38; TRIP6; PITX1; ENO1; ID2; MSX1; FLNA; EMX2; HOXC6
Down-regulation 63 MEOX1; EN2; LMCD1; TLE1; E2F8; WT1; ZBED2; SPIB; MYBL1; SSX1; OSR2; ZIC3; ZNF536; PBX1; TRIM24; ELF5; NR4A1; SOX13; MNDA; ZBTB16; ST18; CRYM; TFEC; NFE2L3; SOX3; ZBTB44; NEUROD1; TCF21; GATA6; NANOG; JUP; HOXD1; TBX3; PHIP; CITED2; TP63; HHEX; NKX3-1; AEBP1; SOX2; NKX2-2; NR5A2; KLF11; TFAP2C; ZBTB20; BHLHE41; BNC2; SALL2; MYCL; ZFPM2; LIN28A; ZNF331; ZNF117; IRF8; FOXF1; CBFA2T3; ERBB4; PBX3; ID4; POU2AF1; TOX3; KDM5D; ZNF586