Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID18024 Gsk-1059615 GSE70138 MCF10A Human 3h 10uM EID0023
Types Number Response transcription factors
Up-regulation 43 TSC22D3; MEF2C; FOXN3; NFE2L1; FLI1; TXNIP; TADA3; TFEB; KLF9; NR1H2; KDM5D; FOXO3; NFKBIA; IKZF1; MEOX2; TRAK1; ZMYND8; KLF2; ATF4; SOX4; HMGB3; HTATIP2; SMARCA2; HOXA5; HBP1; RXRA; IRX5; BCL6; TRIM22; NFIB; ID2; TAF10; NR1D2; SAP30; NPM1; INSR; TRPS1; ZBTB38; HLTF; BMI1; ZIC1; MAFB; HOXC6
Down-regulation 57 FOSL1; MYC; HMGA2; SERTAD2; ETS1; PPRC1; JUNB; TBP; KLF10; HES1; SOX9; FHL2; ETV5; SF1; ADRB2; EGR1; MAFF; OLIG2; EGR2; NR4A2; NR4A1; KDM5C; NAB2; HOXA10; FOXD1; POLR2A; PDLIM1; EGR3; ST18; WT1; NR0B1; BHLHE40; JUN; ATF3; ESR1; ETS2; CHD7; NFE2; SOX13; ZEB1; TCF21; HHEX; CEBPZ; NANOG; FOXF1; IRF6; FOXF2; TFAP2C; INSM1; SNAI2; PEG3; HOXB2; CREB1; SOX17; EED; ID4; MEIS2