Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID18004 Alvocidib GSE70138 MCF10A Human 3h 0.37uM EID0023
Types Number Response transcription factors
Up-regulation 15 HSBP1; AEBP1; TGFB1I1; RBPMS; SATB1; THAP11; BBX; SMARCA1; KAT2B; TWIST1; LEF1; ZNF423; TCF4; NR2F6; MEIS2
Down-regulation 89 MYC; NFKBIA; FOSL1; ADRB2; ZFP36L2; NRIP1; JUNB; HES1; TAF1D; SERTAD2; ARID4B; SUV39H1; BCL10; NFIL3; RNF111; CEBPB; HOXA1; CCNA2; SMAD7; ETS2; BTG1; TSC22D2; POLR3F; PLAGL2; SMAD3; HOXA5; TGS1; CDK7; ZNF267; HOXA10; CHD1; TAF5; NPAT; KAT6A; EGR2; CCDC59; TGIF1; FHL2; ZNF3; ZNF410; BACH1; ELF4; SOX9; CEBPD; ZNF217; AHR; FOXO3; BAZ1A; RUNX3; RYBP; EGR3; RNF138; YEATS4; CITED2; ZNF281; CCNE1; MED17; KLF10; DDIT3; SAP30; KLF4; ZNF22; FOXC1; ATF3; TOB1; SNAI2; NR4A1; MNDA; ZBTB16; ELF1; SATB2; ZEB2; NRBF2; TP63; TFAP2C; JUND; FOXO1; TRIM29; EGR1; TSC22D1; REL; KLF6; BHLHE41; NR4A2; GATA6; ID1; MAFB; WT1; EED