Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17996 Geldanamycin GSE70138 MCF10A Human 3h 3.33uM EID0022
Types Number Response transcription factors
Up-regulation 57 DDIT3; MNAT1; SMARCA2; XBP1; TMF1; ING3; BHLHE40; BRD8; ZBTB11; NFE2L1; NRBF2; CEBPG; ATF4; COPS2; PIR; NR2F2; NEDD8; MTDH; KAT7; ZBTB38; BBX; CCDC59; ELF1; BCLAF1; KDM2A; RNF6; MEF2A; RBM14; BASP1; ITGB3BP; DNMT3B; DNAJC1; IRX5; TOB1; BMI1; CRY1; MED1; SIX1; NR1D2; MAGED1; SFPQ; CTR9; RBBP4; CALR; ERBB2; STAT6; SUB1; PTTG1; HLTF; KDM5D; HOXC10; HOXC6; FOXC1; TRIP6; HTATIP2; PURA; CREB1
Down-regulation 268 FOSL1; MYC; HES1; EHMT1; ARNT2; TCEA2; E4F1; FOXK2; TGIF2; TP73; MBD3; FOXI1; NEUROG2; RXRG; EGR1; TAF7L; E2F4; ZXDC; GATA1; ZNF324; CAPN15; HIPK2; FOXC2; MLLT1; RFX1; LYL1; SOX14; TAF6L; PITX3; PRDM16; POU3F4; SOX17; PBX3; VENTX; POU1F1; CEBPD; POU3F3; ZEB1; HOXB1; ZNF665; TFAP2C; ZNF154; HOXB8; MED14; HIC2; CDX4; ID1; NFATC4; IRX4; PCGF3; ZHX2; CREM; MAML3; PRRX1; FEZF2; DLX4; ZNF671; TFDP3; ZSCAN9; HOXD12; GTF2I; HIC1; PRDM9; FOXA2; NR0B2; LIN28A; ESRRB; OVOL1; ARID3B; FOXB1; ZNF80; TFAP2A; EYA1; RARG; ZNF701; POU4F3; FOXH1; FOXD3; TCF4; EGR2; DLX5; HOXD3; ZFP69B; TULP1; EMX1; TBX5; NPAS2; ALX4; ZNF257; TCF21; ZNF440; PLAG1; ZIC3; SOX21; NEUROD4; POU6F2; TGFB1; ZNF180; TRIM24; PRDM12; SCRT1; BNC1; MECOM; SOX2; NFE2L3; ZNF667; PAX4; SRY; SIX3; DDX17; ZNF268; MECP2; GBX1; TAF4B; PROP1; CITED1; ANKRD1; NCOA3; CBX2; ZNF573; SOX18; GBX2; CDIP1; ZFHX4; SNAI2; TSC22D3; SOX11; REL; POU2F3; ZNF415; ZBTB44; RBPJL; NKX3-2; ZNF544; EN1; CSDC2; TEF; ARID3A; ZNF654; TEAD4; HOXD1; SOX3; NFE2; ZBTB3; HNF4G; TWIST1; GLI2; CHD2; ZNF117; RORC; E2F5; NR1H4; THRB; GFI1B; PGR; MED12; ZNF334; ZNF682; NANOG; SOHLH2; ZNF224; CARF; ZFPM2; ZNF75D; ZNF141; PRDM14; KLF3; NR4A3; MYRF; TAL1; SPDEF; BNC2; CUX2; NR4A1; BARX1; ZBTB16; ELF4; HDAC9; ZNF235; ETV5; ZNF611; HOXB5; LHX3; BRWD1; SOX5; WT1; BHLHE41; MEIS2; ZNF43; VGLL1; FOXF2; CHD9; ZSCAN18; ID4; ZFP36L2; ZNF160; CERS4; ZNF721; ZNF423; BCL11A; PLAGL1; ZNF273; ZNF93; ARID5B; SOX13; HLX; ZNF85; ZNF331; AEBP1; SMAD6; CDX1; PKNOX2; NR2F6; NFATC1; TOX3; FOXG1; TLE2; ZNF512B; BACH2; ELF3; SOX4; HHEX; FOXO1; NKX2-1; PBX1; TRIM22; KLF1; EGR3; HOXB2; WNT4; NR5A2; SOX9; INSR; ZNF467; ZNF589; CBFA2T3; SIX2; KAT2B; MEIS1; ZNF217; HIRA; TLE4; FOXF1; SSBP3; ZBTB20; NEUROD1; KLF6; NFATC3; SMARCA1; TCF7L2; HOXA10; ZFP36L1; MYBL1; MYCL; NR4A2; ZNF91; NR1H2; SMAD1; FOS; KLF4; MEF2C; SSBP2; ESR1; EMX2; IRF8; JUP; HOXB6; PEG3