Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17984 Withaferin-a GSE70138 MCF10A Human 3h 3.33uM EID0022
Types Number Response transcription factors
Up-regulation 93 NR3C1; E2F2; GATA3; GABPB1; ERG; SOX15; YBX2; CLOCK; PHOX2B; TLE4; CREM; ZNF473; PAX9; JUN; BARX2; HBP1; GTF2A1; SSX1; XBP1; PRRX2; ZNF394; TOX; STAT4; ATF3; MXD1; GATAD2A; CEBPZ; TFEC; HDAC5; NR2E1; RARG; GBX2; EGR1; ZNF175; FOXF2; TULP3; FLI1; CBX2; CD3D; HAND1; WWC1; NFIX; ERBB4; JUND; WWTR1; ADRB2; TBX3; FOS; RBPMS; PCGF1; ISL1; PFDN5; DDIT3; LHX3; SUPT3H; SIX3; HOXD1; JUNB; MAFB; TCF4; KLF3; FOXO1; TCF7L1; RBM39; VGLL1; MEIS2; FOXE1; PAX6; CERS4; TFAP2C; NANOG; TBL1X; ZNF423; AEBP1; SMAD1; HIRA; CREB1; ZNF266; KLF2; HIC2; SIX2; ZNF43; PHIP; ERBB2; MYCL; BCL11A; ELF5; POU2AF1; GATA6; CITED2; JUP; IRF6; ZNF91
Down-regulation 45 MYC; HES1; HMGA2; ATF1; NFKBIA; NFIL3; REPIN1; HOXA10; ZNF226; BASP1; PA2G4; RERE; SMAD3; IKBKAP; BHLHE40; ZNF32; KLF10; EGR2; TAF1D; SOX4; AHR; MYRF; ETV5; PRKDC; VDR; HOXB6; NCOR2; TGFB1; BAZ1A; BIRC2; RFX5; SNAI2; APEX1; NFIB; ZIC1; TWIST1; NRIP1; HOXA5; FLNA; PPARG; SPEN; TOX3; MYB; EGR3; TXNIP