Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17983 Withaferin-a GSE70138 MCF10A Human 3h 10uM EID0022
Types Number Response transcription factors
Up-regulation 223 SUV39H1; EGR1; PHIP; PRDM1; TAF1A; TFEC; NR4A1; SALL1; TLE4; BHLHE41; KDM5A; HIVEP1; DYRK1B; JUN; DAXX; FOS; FOXL2; CREM; MEF2D; PAWR; ATF3; PBX1; TFEB; SRF; ZNF140; BAZ2B; TCF4; ZNF710; ID4; BCOR; WWTR1; KLF11; ARID3A; WNT4; POU2F2; WWP1; DACH1; FOXE1; ZNF671; CAMTA2; HIC2; SMARCC2; GMEB2; XBP1; ESRRB; PAX6; IRF1; ZNF254; FOXH1; ZNF136; RAX; GATA2; TBX3; ZIC3; HINFP; ZNF174; OSR2; TAL1; ERBB4; IRF2; LMO1; MXD1; JUNB; MEIS1; SOX13; NFE2L3; ID1; SALL2; HNF4G; ZNF93; HESX1; ZFP69B; BAZ2A; IRF8; ZNF34; REL; TAF11; GFI1B; WT1; ZNF154; MAML3; TRIM24; ZFPM2; SOX17; RAD21; NAB2; ZNF10; PRDM14; ZNF623; KAT2B; ZNF512B; LIN28A; SOHLH2; GATA6; ZEB1; HEY2; PAX1; HBP1; ZBTB20; ZNF426; ZNF711; ZNF516; BNC2; HIRA; HDAC9; RBPMS; PRDM2; CIR1; IRF7; NHLH2; TRPS1; ZNF394; SP100; ESR1; ZNF75D; NKX2-1; ZNF432; HOXB1; NFE2; SOX3; EGR2; GATA1; CREB1; NANOG; BRWD1; NFATC4; ZNF816; CDIP1; CAMTA1; TCF7L1; FOSB; PNRC1; CBX7; ZNF682; ZBED2; NR4A3; E2F5; SOX18; MKL1; L3MBTL1; MEIS2; TLE2; ZNF586; ZNF175; RERE; GLI2; SOX5; EGR4; ATOH1; CUX2; SUMO1; SPI1; ELF4; NEUROD1; TFAP2C; PEG3; ING4; EP300; IRF4; ZNF430; ZNF133; FOXA2; IRF9; CITED1; SOX2; NR2F1; PRDM12; HHEX; SMAD6; ZNF652; ATF7IP; TSC22D2; CERS4; ZEB2; BCL3; SPIB; ZNF165; JAK2; LHX3; POU2AF1; ZNF573; NCOA2; ZBED1; ZNF589; BASP1; CBX4; TOX; ZNF117; ZNF415; FOXF2; NR5A2; ZSCAN31; ZNF91; BRD7; KLF4; CBFA2T3; NFATC3; SPDEF; ZNF131; ZMYND8; RSF1; TCF7L2; VGLL1; MEF2C; NR4A2; ZNF43; TFDP2; DLX2; KLF10; TULP3; CITED2; MNDA; MYCL; INSM1; NKX2-2; DLX5; TCF21; MYRF; SPEN; ZSCAN18; EGR3; JUP; EMX2
Down-regulation 62 MYC; TCERG1; ABL1; KLF5; ZMIZ2; LITAF; ATF1; NONO; VEZF1; FOXK2; NFIL3; HMGB1; SSRP1; ATF5; NCOA4; HDAC6; MAGED1; RBBP4; SIX2; ZNF226; MLX; NFKBIA; HES1; PBRM1; ITGB3BP; YBX1; HNRNPD; MYCBP; NR2F2; SMARCA2; FOXC1; MKL2; ADRB2; KLF9; BRD8; ZBTB18; KLF2; THAP11; RHOA; SOX4; SMAD7; CBFB; SMAD2; ELF1; TRIM28; RUVBL2; ENO1; SREBF1; SMARCD3; GTF3A; NUP62; EYA2; SMAD3; SATB1; YBX3; HOXC6; ELK3; FOXD1; TLE1; TXNIP; MYB; HOXA5