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Overview Perturbagen Expression Profiles Transcriptional Responses
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Overview Perturbagen Expression Profiles Transcriptional Responses
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Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17978 Mitoxantrone GSE70138 MCF10A Human 3h 3.33uM EID0022
Types Number Response transcription factors
Up-regulation 61 EGR1; ZNF226; MAGED1; SMARCA2; REPIN1; TFAM; MEF2A; ZNF468; NR2F2; YBX1; PIAS2; HIPK3; ZMIZ1; TAF10; SMARCE1; TGFB1I1; CTNNB1; BMI1; PCGF2; CRY1; NFIB; EDF1; CTR9; NCOR2; RUNX1; JUN; RUVBL2; HSBP1; TRIM32; RBBP4; ID2; TP53; ELF1; ING3; TRIM28; ASCL1; HOXC6; RBPMS; ENO1; FOSB; SMAD5; PSIP1; THAP11; FOS; SFPQ; KDM2A; TRIP6; ZBTB38; HTATIP2; RFX5; HOXC10; TRIM16; PIR; ATF5; MAFB; BASP1; KDM5D; SUB1; MYB; ZBTB18; PUF60
Down-regulation 231 MYC; TAF1A; FOSL1; TFAP2A; ADRB2; HMGA2; SOX13; ARNT2; PRDM10; HMG20B; MYRF; ZNF354A; STAT4; BNC1; PCGF3; CHD9; E4F1; IRX4; ABL1; ZNF202; ZNF117; BRWD1; RORA; DDX17; FOXF2; LIN28A; TAF5; POU2AF1; HIC2; MYBL1; ARID5B; NCOA3; ZNF232; CREM; EZH1; ZFP2; KLF13; ZBTB7A; CEBPD; ARID3B; ZNF692; TP73; NFIC; CAMTA2; ZHX2; FOXH1; ZKSCAN3; BRD4; ZBTB44; NANOG; PIAS1; TCF21; ZNF362; MXI1; CUX2; ZNF180; NR1H4; SNAI2; ZIC3; ZNF654; TFAP2C; WT1; ERBB4; HMBOX1; NFATC4; HOXD1; TCEA2; MECP2; FOXL2; NEUROG2; HOXB1; SOX17; ZBTB3; ZNF33B; ZNF257; ZNF410; FEZF2; PHIP; NR4A3; ZNF500; THAP7; ZNF573; CBX7; EMX1; POU4F3; DLX4; GFI1; GATA1; HESX1; PRDM12; ZNF682; MKL2; NR5A2; SOX21; BARX1; KLF3; ZNF219; L3MBTL1; CEBPE; SOX2; ZNF671; TBX21; KAT2B; PBX2; BCOR; ZFP36L1; ZNF141; ZNF440; BARX2; ZNF235; SMAD3; ZNF423; HOXA4; SRY; ZNF93; ZNF665; FOXF1; PAXBP1; ZNF345; PIAS4; TCF4; MAFF; HLF; POU6F2; BHLHE40; SALL1; PLAGL1; ZNF711; TERF1; ZNF75D; ATOH1; CBFA2T2; ZNF334; BNC2; SHOX2; BANP; TSC22D2; ZKSCAN4; CCNE1; ZNF667; ZNF43; PRDM2; ID1; ELF4; BCL11A; GFI1B; BRD7; PAX5; TBX3; SMARCB1; ZNF586; VGLL1; PRDM14; MEOX1; ZNF589; ZBTB20; NFIL3; BACH2; NR0B1; IL16; SMAD1; WWC1; FOXG1; RCOR1; NFATC3; CBX4; SSBP3; CENPF; NEUROD1; ZBTB16; SCAI; CHD2; ZNF248; ZEB1; SPI1; IRF9; SOX3; ZNF131; ZNF253; NFE2; CBFA2T3; TULP3; NCOA2; PKNOX2; ZNF623; ZNF415; ZNF217; SPIB; SMARCA1; CREG1; EP300; REL; SIX3; CRYM; MEIS2; CITED2; HOXB5; RUNX3; PEG3; ZNF12; CREB1; TP63; ATF3; TRIB3; TWIST1; MAF; SALL2; ZBED2; TFDP2; ETS1; NLK; ESR1; ARID4B; JAK2; HOXA10; PBX3; MYCL; MEIS1; NR2F1; ZNF331; GATA6; ARID1A; HOXB2; HIRA; ZNF91; KLF4; TRIM29; HHEX; JUP; VPS72; INSM1
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