Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17961 Y-39983 GSE70138 MCF10A Human 3h 1.11uM EID0022
Types Number Response transcription factors
Up-regulation 105 PAX8; SMARCA2; ORC2; ZNF302; SAP30; HES1; MED7; BRIP1; HOXC10; TBX2; LIMD1; ZEB2; ID2; HOXC6; NEDD8; PPARGC1A; TEAD1; TSC22D2; HIPK3; NR2F2; RNF14; ELF1; ZNF468; ZNF226; TRIM32; ZNF146; NPM1; AFF1; PSPC1; ZNF23; PIAS2; PURA; NRBF2; ZBTB1; DDX5; TSC22D1; SP3; HIVEP2; MITF; FLNA; BLM; KAT6B; RCOR3; MAX; SIM2; CBX6; CEBPD; ZMYND11; PITX1; UBE2B; NFYC; RNF10; ING2; SATB1; PBRM1; XBP1; SAP18; TBL1XR1; TBL1X; TOB1; HDAC7; GTF2I; WWC1; RNF141; MEOX1; STAT6; CTNNB1; YWHAB; PIR; TAF10; ZNF131; ELK3; HOXA10; GTF3A; MEIS1; HSF2; RHOA; FOXC1; ZBTB18; ZNF430; SMAD3; SMARCE1; HLTF; MTF2; PHF20; ZNF528; CEBPB; CENPF; PDLIM1; EYA2; KLF9; PFDN5; ADRB2; ECD; LEF1; ASCL1; RBBP4; CARHSP1; ZBTB38; EGR2; ZIC1; DACH1; BASP1; EMX2; CRK
Down-regulation 199 ADNP2; IRF7; POU2AF1; ILF2; USP16; CAMTA1; KLF13; FOXA2; THAP4; ZIC3; ZEB1; SNAPC4; ARID5A; ARNT2; HEY1; ABT1; E2F4; E2F5; SMARCD1; ENY2; MED16; FOXH1; HMGA2; ATF5; HSF4; PCGF3; CREB3; GATA1; HOXA5; BCL11A; RRN3; HOXA3; TCF7L2; AEBP1; NFE2L3; MNDA; ZNF444; ATOH1; ZNF544; PBX3; NFIC; ZFPM2; CDK9; HSF1; ZNF688; RELA; GBX2; CREG1; GATA6; ZNF423; NFATC4; TULP1; LIN28A; IRF1; NR5A2; PAX6; ZNF512B; ETV5; CDIP1; ZNF215; ARRB1; ZNF711; STAT4; CEBPE; HOXA4; HHEX; MAFF; CHD4; BARX1; ING4; GLI2; PRDM14; TEAD3; MEIS2; PUF60; CDX2; HIVEP1; CBX4; ZSCAN9; ZNF34; SNAI2; PRDM1; NFIX; CTCF; HOXA2; ETV4; TCEA2; TP73; NANOG; RORA; BNC2; NHLH1; BACH1; MED17; SP100; PAXBP1; TAL1; TRIB3; SUPT3H; NR0B2; FEZF2; TCF7L1; FOXI1; NR1I2; EN1; MED14; SOX21; ZNF154; ZNF586; MKL2; ID3; TULP3; ZFHX4; ZNF394; POU6F2; HEY2; SMAD1; CHD9; HBP1; TGFB1; HOXD1; GFI1B; SPDEF; CEBPZ; KAT2B; RBFOX2; DLX2; THRA; FOXF2; SMARCA1; BACH2; RING1; PIAS4; SATB2; SSBP3; RAD21; HIC2; MAFB; HOXB5; HOXB6; SALL2; NFATC3; INSM1; KLF7; ZNF175; SOX3; MYRF; YBX3; ZBTB16; MYCL; SUB1; ZNF117; NR4A3; PBX1; FOXF1; SOX17; SOX2; REL; TDP2; NR2F6; CHD7; ARID5B; ZNF232; PLAGL1; PRRX1; PHIP; ERBB4; NLK; IRF9; TCF4; NR1H2; SOX9; LOXL2; NFKBIA; BTG1; PNRC1; TOX3; TLE1; TFAP2C; APEX1; SCAND1; MEF2C; NEUROD1; TRIP6; ELF5; SPIB; TCEA1; SOX11; KLF11; RBBP8; IRF6; TWIST1; ESR1; ATF3; MSX1; VPS72; IKZF1; ZNF91; HOXB2