Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17950 Torin-1 GSE70138 MCF10A Human 3h 0.37uM EID0022
Types Number Response transcription factors
Up-regulation 82 GATA2; SMARCA2; CTNNB1; KDM5B; EGR1; ASCL1; FLNA; SAP30; ADRB2; ARNT; UBE2B; MNAT1; CEBPD; ELF1; TGIF1; NCOR2; RFX5; RBPMS; CITED2; ZBTB16; SMAD4; URI1; TEAD1; FOXO3; FOXC1; HIPK3; IRX5; PHOX2B; PPARGC1A; CEBPZ; PRKDC; WWC1; EDF1; ARID5B; NR1D2; BHLHE40; ZNF217; NFIB; BMI1; TGFB1I1; CERS6; LMCD1; HDAC4; NCOA3; ELF3; ZNF131; LPIN2; HIVEP2; SATB1; SMAD2; SLC2A4RG; KLF10; BANP; RCOR1; PTRF; NCOA1; ATF4; ZNF532; NCOA2; ZBTB38; BCL3; HMGA1; HOXC10; TBL1X; NFKBIA; CALR; HMGB2; HLTF; PDLIM1; TWIST1; HOXC6; OSR2; TOX; FOXG1; ISL1; MAFB; AEBP1; HOXA5; PITX1; WT1; TCEA1; BASP1
Down-regulation 104 SUZ12; ZNF35; ZNF557; MED17; CHD8; SMARCD1; SMAD1; NKRF; NFYA; TAF11; IRF9; YAP1; HMBOX1; SALL1; ZNF432; ADNP2; STAT1; ARID1A; FOXF1; RBPJ; MEOX1; TAF5; ERG; FOXI1; DLX5; HIC2; RFXANK; ZNF394; ZNF3; E2F2; NFE2; ZBTB7A; ACTL6A; RYBP; ZNF195; RARB; SMARCC2; NAB1; SCAND1; TLE4; ZNF544; MNDA; AR; TAF5L; GLI2; CTBP2; ZNF266; TRIB3; ZNF112; FOSB; PSMC3; ZIC3; ID4; TCF4; DACH1; FOXF2; LITAF; SSX1; TLE1; SOX2; CCNE1; SIX3; HEY1; VDR; TCF21; IFI16; KLF1; KLF13; NR4A1; MEOX2; TULP3; MECOM; MYB; ZNF611; SMAD3; ZBTB18; CBFA2T3; ARNT2; PAX6; KAT2B; JUND; EGR3; DLX2; SIX2; PBX1; SPDEF; HHEX; KLF4; ZKSCAN1; EED; ZEB1; HOXB2; ZBTB20; JUP; SSBP2; FOS; MTF2; HOXB6; ID3; TOX3; ZNF589; CREB1; ZNF91; ZNF331