Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID17937	Gsk-2126458	GSE70138	MCF10A	Human	3h	1.11uM	EID0022

Response Information :

Types	Number	Response transcription factors
Up-regulation	78	TSC22D3; NR3C1; MXD4; TBX2; NR2F2; UBE2B; SETD2; ID2; RFC1; MBD2; POU4F1; HOXC6; SMAD4; SOX4; MEF2A; CDK7; STAT6; PBRM1; BAZ2B; TLE1; PSPC1; RERE; BRD3; ARNTL; NFIL3; BRCA1; HBP1; SMAD5; NFKBIA; DBP; CTR9; CUX1; HMGN3; NCOA1; JARID2; RBBP4; YBX1; RUVBL2; ELF1; SMARCA2; BRD8; RNF141; ZNF189; ING3; RBPMS; NR1D2; HOXB7; TAF10; MTDH; BASP1; ATF7IP; NR1H3; FOXC1; BCLAF1; SAP30; AFF1; HDAC1; TRIM16; HTATIP2; MSX1; BTG1; PTTG1; HOXA5; NFIB; ATF4; ELF3; RBBP8; HLTF; MAGED1; FLNA; ERBB2; OSR2; ZBTB38; PSIP1; CREG1; KLF2; NRIP1; PUF60
Down-regulation	226	FOSL1; MYC; HMGA2; TAF1A; EGR1; CAPN15; JUN; PPRC1; LIN28A; MNX1; ILF2; TP73; SOX13; TFAP2A; ARNT2; ZBTB7A; E2F4; ZNF544; UTF1; CDK9; MAFF; TGIF2; BARX1; HOXD3; NFATC4; GATA4; ETV5; ZNF692; ZNF254; PKNOX2; ZNF423; HMGXB4; NEUROG2; TAL1; FOXA2; MLLT1; ZNF257; ZNF682; ZNF557; POU1F1; KAT2A; TCEA2; ZNF442; RYBP; FEZF2; MYRF; PEG3; NEUROG3; EGR4; FOXL2; NPAS1; SMARCB1; NR0B2; EN1; HLX; ZNF669; ZNF85; TAF1C; NFE2L3; ZNF135; ZNF155; ZFP69B; PRDM1; ZNF202; HES1; NANOG; ZNF3; SOX14; ZNF273; HIC1; SCRT1; SOX1; RFX1; BRD4; CREB5; ZNF180; ZNF749; IKZF3; ZNF549; NEUROD1; ZNF141; SOX17; ZNF334; TLX3; ZNF345; ZNF43; TCF21; FOXB1; SRY; ZNF500; FOXH1; SOX5; SOX18; ZNF124; TEAD4; ZNF780B; NFE2; SALL1; CSDC2; DMRT1; IRF9; ZIC3; HIC2; ZNF573; GFI1B; BNC1; ZNF675; EMX1; SNAPC4; LDB1; ZNF225; LZTR1; ZNF362; TBX1; SIX6; ZNF222; CUX2; ZNF667; HHEX; ANKRD1; ZFP36L1; MYBL1; TSC22D2; ZFPM2; OLIG2; SPDEF; ATN1; RBPJ; ZBED2; POU6F2; NKX3-2; PROX1; PCGF3; SPI1; ZNF350; ZNF415; ERBB4; HDAC9; SNAI2; ZSCAN18; LOXL2; ZNF654; ZNF74; HOXB2; GATA1; SOX2; BHLHE40; TULP3; ZNF665; ZNF253; KAT2B; ZNF165; CCNE1; MAF; ZHX2; ZNF467; ETS1; BHLHE41; ZIC1; SOX21; GLI2; NR1H4; ZNF91; ZEB1; KLF11; WT1; SOX3; BRD7; ZNF93; HLF; TWIST1; ZNF232; PBX1; BNC2; EGR2; JUND; JAK2; TULP4; REL; VGLL1; MYCN; TDP2; SIX3; SATB2; BCL11A; ZNF331; ASCL1; NFATC3; CBFA2T3; PRRX1; PBX3; KLF1; ADRB2; FOXF1; TRIB3; ZNF117; GATA2; KLF4; NR4A1; EHF; SHOX2; BACH2; TGFB1; TBX3; ST18; NR1H2; ID4; SOX9; HOXD1; VPS72; NR5A2; NKX2-2; SALL2; EGR3; TOX3; IRF6; INSM1; IRF8; ZNF589; NR2F6; GATA6; AEBP1; CREB1; SOX11; FOS; MEIS2