Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17932 Zstk-474 GSE70138 MCF10A Human 3h 0.37uM EID0022
Types Number Response transcription factors
Up-regulation 49 TSC22D3; BHLHE40; PPARG; FOXN3; TAF10; TGIF1; ZMIZ1; CNBP; HBP1; MBD2; SMARCA2; NR1D2; NEDD8; UBE2B; NFIB; SAP30; WWTR1; JUND; TOB1; LPIN2; SMAD7; CREM; BCL11B; ZBTB38; FOSL2; DDIT3; TRIM16; ATF3; CEBPB; HMGN3; INSR; AHR; ZNF217; RBPMS; HOXA5; PSIP1; ELF1; MECOM; ELK3; HLTF; PTTG1; KLF9; PDLIM1; SCAND1; HOXC6; TLE1; ZBTB18; FOXJ3; BASP1
Down-regulation 72 FOSL1; HMBOX1; JUN; PAXBP1; NKRF; ZNF692; BRD4; KAT2B; ZSCAN9; AR; MBD4; MED13; HOXB2; ZNF3; MED17; TCEA2; PGR; CREB3L2; ZBTB44; TSC22D1; THAP7; NKX3-1; SNAPC4; ZNF34; CBFA2T3; CHD4; HOXB5; RYBP; MECP2; ZNF235; BRWD1; PKNOX2; ID1; ASCL1; SOX3; SALL1; KLF1; MEIS1; HDAC9; KLF13; DLX5; ESR1; ZNF512B; ZBTB20; VPS72; NFE2; CREB1; IRF8; HOXA10; HOXB6; SOX2; TRIM22; MSX1; PBX3; IRF9; ZNF91; NR1H2; JAK2; SPDEF; AEBP1; ZNF43; ZNF117; WT1; BCL11A; FOS; SATB1; SMAD1; SOX17; PEG3; INSM1; ZNF589; TOX3