Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17903 Azd-5438 GSE70138 MCF10A Human 3h 0.12uM EID0022
Types Number Response transcription factors
Up-regulation 22 HES1; TRIM16; NR2F2; MYT1L; RNF4; SIAH2; PIR; ELF1; CTR9; KLF10; JARID2; AFF1; SUB1; BASP1; ZBTB38; FOXJ3; HTATIP2; MSX1; HOXC6; CREG1; NRIP1; LEF1
Down-regulation 76 TSC22D3; CEBPG; WT1; NFE2L3; MED20; ZNF586; BACH1; FOXL2; STAT2; RBPJ; PCGF3; KLF4; TCF4; HIC2; TFAP2C; ZNF665; KLF3; NFATC4; NAB2; NANOG; CHD9; SSBP3; ZNF224; TWIST1; TRIM29; ZNF345; SOX5; ZNF117; ID4; KLF13; CCNE1; PAWR; PRRX1; DLX5; TCF21; POU2AF1; PHIP; BTG1; HBP1; KLF6; TLE4; GATA6; MYCL; ZHX2; ZNF165; LMCD1; SPDEF; ZNF217; ZNF93; HOXD1; SMARCA1; TRPS1; SNAI2; CBFA2T3; SOX4; BACH2; ZNF331; KLF5; SOX2; IRF9; JAK2; ZNF589; ZFPM2; BHLHE41; SOX17; CITED2; PBX3; NFATC3; ATF3; BCL11A; EMX2; MYRF; ZSCAN18; ZNF91; NR4A2; CREB1