Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID17876	Canertinib	GSE70138	MCF10A	Human	3h	3.33uM	EID0022

Response Information :

Types	Number	Response transcription factors
Up-regulation	113	PAX8; TSC22D3; FOXO3; ZNF302; BRCA1; POU5F1B; MEIS1; DNMT3B; RORA; FOXJ2; SMARCA2; ZNF226; ID2; XBP1; ZNF222; ZMIZ1; NKRF; THAP10; PKNOX1; GTF2IRD1; ZSCAN31; TRIM29; FHL5; KLF2; HMBOX1; NR2E1; JUND; ZNF16; ZNF669; TCF25; ATF3; PHIP; IRF5; FOXO4; RBBP4; LITAF; PHOX2A; PIR; HIPK1; TRIM24; E2F2; JAK2; CBX7; CTNNB1; MITF; PEG3; ZNF721; TTF2; ARID3A; NFIX; SMARCA4; E2F8; DAXX; BNC2; FOSL2; TEAD3; SMAD5; ZNF32; FUBP1; BCL3; ZNF665; KLF7; PBX1; KDM5D; BRD8; PCGF2; ZNF140; NANOG; NCOA3; TCF7; AHR; CITED1; ZNF536; PNRC1; SOX4; EP300; SALL1; HOXC10; MYCN; MDM2; CEBPB; KLF4; CEBPZ; MAFB; EMX2; TRIM16; TFAP2C; VGLL1; NR1H4; HIRA; ZNF93; ZNF467; CBX3; CRYM; TBL1X; PAX6; ELF1; JARID2; ZNF217; MAGED1; CITED2; TBX3; SALL2; FOXJ3; ISL1; AFF1; NFAT5; WT1; HOXA5; LEF1; BTG1; ESR1; HOXC6
Down-regulation	70	FOSL1; MYC; HMGA2; FOXK2; PPRC1; MBD2; SIRT7; EGR1; TGFB1I1; ADRB2; ATF5; ZNF281; PAX5; AATF; STAT3; SMAD7; MEN1; ZEB1; IFI16; TCF7L1; SF1; SERTAD2; ZNF22; NAB1; KLF13; CHD7; ZFP36L1; EHF; RLF; PTRF; BHLHE40; RUNX3; RELA; CTBP2; NKX2-1; TGFB1; RYBP; EGR3; YAP1; E2F5; EGR2; ZBED2; BCL10; SATB2; NFKBIA; NRIP1; NR4A2; WWTR1; ETV1; RNF138; IL16; MYB; ZNF512B; ZFP36L2; PDLIM1; TCF7L2; THAP11; MYCL; TOX; POU2AF1; ID3; MYBL1; SSBP2; FOS; HOXB2; HOXB6; FOXD1; SNAI2; ELK3; TOX3