Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID17873	Afatinib	GSE70138	MCF10A	Human	3h	0.12uM	EID0022

Response Information :

Types	Number	Response transcription factors
Up-regulation	43	TSC22D3; EGR1; ID2; PPARG; RBPMS; MITF; BCL6; TFEC; NR1H3; MEOX2; IRF5; HIPK3; PROX1; MAF; TRIM16; BASP1; ZSCAN31; PIR; TRIM29; PAX6; MNDA; TAF10; TCF4; SSX1; KLF9; TOB1; TLE4; MAFB; PITX1; SCAND1; ZEB2; PBX1; TRIM22; BHLHE41; ST18; ERBB2; ATF3; TP63; HOXC6; HOXB7; TRIP6; TXNIP; HEY1
Down-regulation	36	FOSL1; MYC; HMGA2; FHL2; PPRC1; AGO2; HES1; STAT1; PAXBP1; BTAF1; ETV5; IRF1; SMAD7; BCL3; KLF10; NKX3-1; ESR1; DLX2; ELK3; BACH2; BIRC2; ASCL1; SATB2; ZNF217; HDAC9; FOXD1; NR4A2; SMAD1; ZFP36L2; RUNX3; TLE1; PEG3; SOX17; CREB1; LEF1; ZNF331