Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID17872	Afatinib	GSE70138	MCF10A	Human	3h	0.37uM	EID0022

Response Information :

Types	Number	Response transcription factors
Up-regulation	41	TSC22D3; SOX2; ID2; PMF1; ECD; TFEC; TRIM22; KAT7; TLE4; BNC2; HMGN3; TLE1; ATF7IP; HOXB7; NFE2L1; DNMT3B; RBPMS; TRIM16; PIR; MAFB; ATF4; ZEB2; ZNF589; HOXD1; NCOA2; ERBB2; LIN28A; IRF8; SREBF1; RFX5; PSIP1; NANOG; TP63; HHEX; GATA6; PBX1; ESR1; SCAND1; JUP; TOX3; NR2F6
Down-regulation	69	FOSL1; MYC; HMGA2; FHL2; EGR1; TSC22D1; EGR4; JUN; EGR3; DDX17; TSC22D2; E2F3; HMBOX1; ATF5; CDK8; SOX11; FOSB; NFE2L2; AGO2; SMARCC2; MAFF; NR4A1; NR4A3; BAZ2B; SKI; STAT1; MGA; RBPJ; SIM2; MEIS1; ZNF165; HDAC4; PFDN5; SP3; DLX2; ZNF12; HMGB2; SIX1; ZNF281; EGR2; VDR; SOX9; ADRB2; KLF13; ZEB1; SMARCA1; EHF; ATF3; NR4A2; ZFP36L1; ZNF43; SIX2; SATB2; AHR; ELF5; ZNF331; PBX3; TCF21; ZIC1; MECOM; NKX2-2; KLF4; TRPS1; WT1; TBX2; FOXF1; INSM1; EMX2; MEIS2