Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID17869	Afatinib	GSE70138	MCF10A	Human	3h	10uM	EID0022

Response Information :

Types	Number	Response transcription factors
Up-regulation	73	TSC22D3; MNAT1; ID2; TBL1XR1; BHLHE41; HBP1; MXI1; TFEC; TP63; THAP10; SP140L; EZH1; LYL1; TFCP2; TOB1; MITF; ID4; SMAD6; GATA6; ZNF652; ZMYND8; TRIM22; PSMC3; FLI1; TLE4; ID1; IRF5; HIRA; PIAS1; OSR2; ZNF430; ZNF394; DDIT3; IRF4; HMGN3; MYCL; GRHL2; TOX; WNT4; IRF9; TGIF1; TCF7L2; IFI16; CRYM; PBX1; ESR1; ZBED2; JUP; BCL6; EYA2; POU2AF1; ASCL1; PNRC1; ZNF91; JAK2; MEIS2; CITED2; ELF3; ST18; SOX17; ZBTB20; TCF4; ATF3; TCEA1; PSIP1; TRIM29; MNDA; MYBL1; MEIS1; VPS72; EMX2; DACH1; TRIB3
Down-regulation	54	FOSL1; MYC; HMGA2; EGR1; FHL2; PPRC1; ADRB2; TSC22D2; ZNF432; EWSR1; GATA4; TFAM; ATF1; UBP1; POLR2A; AGO2; NFKB1; MED1; SOX9; NKX3-1; CREM; EDF1; ETS2; HOXA10; HES1; CRY1; HLX; RBPJ; CBFB; SMARCA1; ELK3; EGR3; FOSL2; ZIC1; CEBPZ; FOXC1; FOSB; ERG; PDLIM1; SATB2; PRKDC; ZBTB18; NRIP1; NFAT5; KLF10; RUNX3; PEG3; SMAD3; FOXD1; PPARG; ETV1; HOXB6; HEY1; KDM5D