Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17867 Celastrol GSE70138 MCF10A Human 3h 0.12uM EID0022
Types Number Response transcription factors
Up-regulation 49 DAXX; SF1; ELF1; RBM14; SAP30; HLTF; TRIM32; VEZF1; ZNF146; IRX5; RBBP7; ELK3; TAF10; NCOR2; RNF6; BRD2; MAFB; SFPQ; SMARCE1; MTDH; CBFB; TRIM28; SMAD2; CTNNB1; ENO1; THAP11; TOB1; BRD8; FLNA; KDM2A; CEBPB; MTA1; GTF3A; RNF10; PURA; HOXC6; MAGED1; PTTG1; PDLIM1; NUP62; FOXJ3; HTATIP2; YWHAB; NFIB; MSX1; AFF1; PITX1; ESR1; PUF60
Down-regulation 146 FOXG1; ZNF350; TCF21; CIITA; THAP7; ZNF268; RORA; ZNF205; EZH2; ZNF669; NEUROG3; TCEA2; TBX10; TP73; HMX1; FOXF1; SIM1; LYL1; JUN; ZNF500; TRIB3; TULP1; CSDC2; LZTR1; SOX13; CRYM; CALCOCO1; PEX14; FOXF2; PHIP; NR4A1; TGIF2; ZBTB44; TLX3; TBX3; TFEB; ZNF74; NFE2L3; FOXN3; CUX2; HOXB1; ZHX2; ZIC3; BNC2; ING4; EMX1; MECOM; ZNF432; MYRF; FEZF2; ZNF586; ZNF154; PROP1; ZNF223; GLI2; SOX21; PIAS1; ZNF345; NFIX; TRIM24; CBX7; ZNF75D; IRF9; RYBP; ARNT2; ZNF91; PLAGL1; HIC2; ZNF141; CBFA2T3; DLX2; EMX2; SIX3; KLF11; SOX3; PBX3; NFATC4; SOX2; NR4A3; CREB3L1; DDIT3; ZNF165; NR1H4; SALL2; ERG; VPS72; HLF; BCL11A; KLF3; FOSB; EGR2; TFEC; SHOX2; TLE4; MXI1; ST18; MEIS2; FOXA1; TOX; PNRC1; ZNF331; SSBP3; GATA6; NANOG; NR5A2; NR4A2; RSF1; IL16; ELF3; SPDEF; HDAC9; NCOA2; CUX1; GATA2; ZBTB20; ZIC1; TOX3; JAK2; HOXD1; ZNF93; WT1; SPIB; NR1H2; SNAI2; ZNF117; BHLHE41; MNDA; MYCL; NFATC3; MEIS1; TCF4; ERBB4; ZNF589; SCAND1; ATF3; DLX5; ZFPM2; SOX17; HOXB2; IRF8; FOS; SSBP2; SATB1; SOX11; INSM1; TBX2