Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID17841	Mk-2206	GSE70138	MCF10A	Human	3h	1.11uM	EID0022

Response Information :

Types	Number	Response transcription factors
Up-regulation	121	RORA; EGR1; MED7; CITED2; TSC22D3; ARID4A; PIAS3; ETS2; NANOG; DMTF1; MNAT1; ADRB2; TMF1; BBX; ZMIZ2; TERF1; HMGB3; ZBTB25; ING3; VEZF1; CHD1; TSC22D4; MITF; ZNF430; BLZF1; TGIF1; BTG1; ZNF107; CCDC59; ID2; CDK7; TSC22D2; HLX; IRF7; DDX54; KLF2; SUPT4H1; WWP1; JARID2; ATF1; POU5F1B; EGR3; ZNF274; TXNIP; HOXC6; KLF6; NR1D2; FOXO3; PHF1; FOXN3; SNIP1; NFYB; ZBTB1; NRBF2; ARNTL; TFAM; MED13; DNMT3B; ZNF394; CTCF; PAWR; FOSL2; EDF1; NCOA4; AFF1; RYBP; CREB3L2; ZNF281; ZNF217; PBXIP1; CEBPZ; HDAC5; NFE2L1; CREBL2; HOXA1; PRKDC; BANP; TRIM22; XBP1; KLF10; RBL2; NCOA1; ELF1; NFAT5; KLF4; KAT6B; IRF8; MAGED1; NPM1; MAF; HBP1; CENPF; HTATIP2; NR1H2; MAFB; TRIM29; ZBTB18; IRF4; KLF9; ERBB2; EGR2; LIN28A; HMGB2; FOXJ3; JAK2; KLF11; SOX4; ARID4B; CD3D; EED; HOXA5; NR4A1; PSIP1; TCF4; ZBTB20; ATF3; KDM5D; EMX2; BASP1; ZNF331; LEF1
Down-regulation	96	SUZ12; LYL1; ZNF473; MECOM; EHF; KAT8; ZBED2; NR2F1; BRDT; ATF5; ATF4; SRCAP; ZNF384; ABL1; SMAD1; NHLH2; PHF20; FOXF2; PCGF1; MAZ; WIZ; FOXA2; SMARCA1; TERF2; YBX2; CNOT1; CAMTA1; TAF10; DLX2; CREG1; E2F5; POU4F1; PRRX2; BAZ2B; HIPK3; PGR; PLAGL2; ZFHX4; RUVBL2; THAP4; NRIP1; NFKBIA; MBD2; NR1H3; OVOL2; VGLL1; NFE2; ST18; HDGF; ZNF133; ETS1; CTBP2; NAB1; SOX11; SMAD6; ZMIZ1; PRPF6; CBFA2T2; TP53; HHEX; NKX2-1; MSX1; SOX9; LITAF; CCNC; FOXF1; TLE1; RBFOX2; HOXD1; THAP11; TOX; PAX6; NEUROD1; FOXG1; HLTF; ARID1A; PITX1; SREBF1; TRIB3; PEG3; ID1; PBX1; JUP; ERBB4; MEIS1; LOXL2; ZEB1; ESR1; SPEN; MYRF; HOXB6; SCAND1; SATB1; FOS; ID4; MEIS2