Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17833 Palbociclib GSE70138 MCF10A Human 3h 10uM EID0022
Types Number Response transcription factors
Up-regulation 58 ETS2; RXRA; PPARGC1A; PBRM1; HIPK3; NCOR2; FLNA; CTNNB1; HDAC4; SOX9; IRX5; TMF1; FOXC1; KAT7; SFPQ; HES1; SAP30; BASP1; KAT8; HMGA1; SIAH2; BRD3; TFEB; KLF10; PCGF2; RNF141; MTA1; RBM14; AFF1; SMAD5; RNF10; RBBP7; MAFB; CEBPD; MEIS1; PIR; ZBTB38; ELF1; DNAJC2; CEBPB; TFEC; STAT6; PITX1; PBX3; NR2F2; ATF4; MED1; SATB1; THAP11; LITAF; ID1; CITED2; KLF5; AHR; TXNIP; SUB1; HOXB6; HOXA5
Down-regulation 104 HMBOX1; IFI16; STAT4; PCGF3; CREBZF; ZNF529; ERG; ATF3; ZXDC; EZH2; ZHX2; ZNF512B; HIC1; VAX2; SP140L; ZNF85; CREM; ELF4; RORA; POLR3C; TRIB3; CCNE1; ZNF544; MYCL; ZNF345; BCOR; SP110; PRPF6; ZNF117; CAMTA1; IRF7; ZNF254; ZNF93; ZBTB20; CBFA2T3; PLAGL1; KLF6; MED14; AEBP1; C1QBP; IL16; E2F2; ZNF500; ZNF10; TCF4; ZNF701; NR4A3; ZNF586; IRF4; ST18; BANP; TSC22D2; GFI1B; ARID4B; CBFA2T2; FOXF2; TAF1D; TLE4; ZNF329; BHLHE41; SOX11; SOX2; BNC2; SPIB; TAL1; ZNF573; JUND; ZFPM2; ZNF711; NR0B1; ZNF160; WT1; SIX1; ZEB1; VGLL1; EHF; MYBL1; KAT2B; LIN28A; TCF21; NANOG; ZNF43; HDAC9; PEG3; DLX5; ZNF217; BACH2; SPDEF; RUNX3; BCL11A; MAF; PHIP; IRF9; TFAP2C; TBL1X; ELF5; POU2AF1; JUP; MEIS2; ZSCAN18; ZNF91; ZNF331; ZBTB18; KDM5D