Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17832 Osi-027 GSE70138 MCF10A Human 3h 0.04uM EID0022
Types Number Response transcription factors
Up-regulation 56 ZNF586; HDAC6; KDM5D; ZNF468; ZNF551; ZNF587; ZNF134; LPIN2; TGIF1; CTNNB1; NR2F2; TSC22D3; ELF1; BHLHE40; FOXC1; CEBPD; BBX; MAGED1; FLNA; ZNF211; ZBTB38; TRAK1; HSF2; ENO1; TRIM28; ERG; RBBP4; TRIM32; ZNF281; ZBTB1; SIAH2; KLF2; RUVBL2; MTA1; NPM1; HOXC6; JARID2; IRX5; MTF2; ELK3; HMGB3; GTF3A; ECD; NR1D2; PTTG1; TBL1X; HOXC10; ERBB2; LITAF; FOXJ3; AFF1; NFIB; PURA; MYB; NRIP1; HOXA5
Down-regulation 186 ARNT2; RXRG; SUZ12; CHD9; E4F1; CDIP1; MED14; ZNF423; KDM5C; CUX2; FOXF2; TGS1; ISL1; ZFHX2; IFI16; FOXN2; TCEA2; CBFA2T3; PKNOX2; SUPT7L; NFE2; PKNOX1; HOXD1; THAP7; CHD8; ZFHX4; E2F4; RAX; NFATC4; ARL2BP; TAL1; MAPK8IP1; BRD4; KAT2B; CDX2; EYA1; SOX11; LZTR1; BNC2; GFI1B; AR; NAB2; KLF4; HOXD3; ZIC3; TCF4; NR4A3; SP4; NEUROD4; LDB1; HOXA3; ZNF219; ST18; ZNF536; HMBOX1; BCL11A; SPI1; CDX1; SOX5; CBX2; PITX2; CREM; HNF4G; GLI2; ESR1; ZKSCAN8; NR4A1; CEBPE; NR1H4; TERF1; NHLH1; CIITA; NFIC; JUN; ILF2; PROP1; ZNF223; ZNF75D; MITF; ZNF334; SOX2; SOX3; FEZF2; LIN28A; GATA1; PRDM14; PRRX1; HOXB1; NR0B2; ZFPM2; E2F5; TOX3; BARX1; ZNF195; GATA6; POU2AF1; ZNF711; NR5A2; THRB; ZNF331; ZHX2; CAMTA1; TCF12; SMARCB1; INSM1; TWIST1; MEIS2; ZNF512B; TLE4; NKX2-1; ZNF345; ZNF34; SHOX2; KLF13; PLAGL1; GLI3; SIX6; SPDEF; NEUROD1; HIC2; ACTL6B; ZNF248; ZEB1; ZNF232; OLIG2; ZNF623; DLX5; ZNF589; HIRA; ZNF117; RSF1; RBFOX2; MYBL1; VPS72; MYCL; NFATC3; AHR; FOXA2; IRF8; KLF11; ZNF141; STAT6; NANOG; TDP2; TCF21; HOXB2; NLK; SALL2; ATF5; CEBPZ; DLX2; AEBP1; SPIB; EGR2; TRIB3; CRYM; KLF1; HLF; NR4A2; ZNF93; TFEC; FOXF1; EMX2; ZFP36L2; CUX1; MECOM; WT1; CCNH; SMARCA1; BHLHE41; BASP1; LOXL2; MEIS1; MYRF; ARID5B; TOX; SNAI2; MAF; MEF2C; SSBP2; DACH1; PBX1; IKZF1; TBX2; ATF3; ID4