Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17815 Bi-2536 GSE70138 MCF10A Human 3h 10uM EID0022
Types Number Response transcription factors
Up-regulation 66 PAX8; EGR1; IKZF1; ID2; FOXO3; CEBPA; TSC22D3; BRD2; SND1; JUNB; FOSB; SMARCA2; TOB1; CERS6; EMX2; ATF3; NR2F2; ZMIZ1; HOXC6; IRF4; BBX; BASP1; DNMT3B; SATB1; SREBF1; TGIF1; HLTF; RBBP7; CARHSP1; AFF1; BHLHE40; BRD8; DNAJC1; SMARCA1; EDF1; CTR9; ZBED2; NR4A1; SSX1; NFIL3; ASCL1; RSF1; NR1D2; CUX1; MTA1; FOS; NPM1; TRIM28; TSC22D1; TLE1; TXNIP; LITAF; MSX1; ELF1; MAGED1; OSR2; ERBB2; KLF2; ESR1; PEG3; CREG1; SUB1; LEF1; HMG20B; HOXA5; JUP
Down-regulation 105 PLAGL2; USP21; MYC; SUZ12; SUV39H1; NR3C1; MDFI; TGFB1; ABT1; ZXDC; CAPN15; IRX4; HMGA2; MYBL1; ZNF202; TGIF2; PCGF1; ZNF232; E2F3; MSC; TCEA2; HIPK2; TP63; ARNT2; ERG; TFAP2C; ZFP64; SETDB1; AGO2; ZNF337; ATF1; MED12; TAF4; HOXA10; ADRB2; ZNF500; HDGF; TRIB3; DLX4; ZNF219; ZNF586; SPI1; PITX2; ZNF512B; ELF4; POU2AF1; HOXA1; MEN1; TOX; NEUROD1; PIAS4; TBX1; CHD7; ZIC3; KLF11; KLF5; TFCP2; HIC2; ZNF175; ZNF133; HLX; ZNF281; EN1; TWIST1; NFATC4; NANOG; FOXF2; SMAD3; HEY1; ZNF22; MXI1; TDP2; OLIG2; BIRC2; ELF5; EGR2; VPS72; MECOM; NUP62; NR0B1; TULP3; ARID5B; CD3D; EHF; ZFP36L2; SATB2; MNDA; SALL2; ZEB1; NKX3-1; NKX2-2; TCF7L2; AHR; TCF21; ZNF43; FOXG1; ERBB4; FOXF1; MEIS2; RUNX3; BCL11A; INSM1; ZNF423; SOX11; SSBP2