Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID17811	Saracatinib	GSE70138	MCF10A	Human	3h	1.11uM	EID0022

Response Information :

Types	Number	Response transcription factors
Up-regulation	144	VGLL4; DMTF1; SOX10; KLF2; EGR1; NFRKB; ZBTB25; PHOX2B; RBPMS; RARA; BBX; TGIF2; SAP30; LMCD1; TRIM29; TMF1; PIAS2; HAND1; NANOG; ANKRD1; CREB3L1; ZNF516; ARID3B; HOXC10; TWIST1; GATA2; DLX4; PHOX2A; LIMD1; RFX2; SSX3; MNAT1; POU4F2; DMRT1; FUBP1; FOXA2; CAPN15; PHF1; SOX13; MAFF; ARID5B; NR1D2; TEAD1; KDM5B; JARID2; LIN28A; KAT7; FOXO3; E2F3; LOXL2; ZNF532; ZNF835; ZNF281; ZNF536; BANP; NR4A3; STAT2; NFIL3; ZNF652; DDX5; TGIF1; SKIL; ZNF654; ZBTB43; SOHLH2; NFE2L1; MITF; ZNF816; PITX1; TRIM24; KDM2A; SMAD5; DNMT3B; GTF2IRD1; CEBPZ; ING2; TFE3; BACH1; BCL3; TBX1; NR1H2; IRF4; ZBTB44; ETS2; IFNB1; MAF; CREBL2; TFAP2C; FOXE1; EN1; RBBP7; KLF9; HLX; ZIM2; BTG1; BHLHE41; HDAC9; HSF2; ZNF528; PPP1R13L; BCL11B; TBL1X; CREM; IRX5; TXNIP; ECD; ZNF552; JAK2; ZNF331; FOXD1; DNAJC1; ZNF721; CEBPB; DDIT3; NKX3-1; SSX1; ISL1; PKNOX2; CBX3; XBP1; SSBP3; TBX3; NFATC1; CITED2; NFAT5; TCEA1; PIR; SMARCD3; NUP62; NR4A1; ZIC1; SPDEF; HLTF; PHIP; FLNA; SNAI2; KLF4; RFX5; NR4A2; GATA6; HOXC6; EGR3; ZBTB18; LEF1
Down-regulation	97	TCERG1; SUZ12; CCNA2; CDK2; RERE; ZNF212; TCF25; BRD4; SMARCC2; HOXA5; ERCC3; ATF1; WWTR1; RNF6; HMGB1; SIRT7; ZNF544; SP140L; ZNF146; RFXANK; PA2G4; DEK; TRIM27; ZBED2; DEAF1; THAP4; CARM1; CHD8; EHF; ATF5; PFDN5; PAX5; DLX2; CREG1; ARID1A; BAZ2B; ZNF432; ZNF274; CNOT1; MKL2; RRN3; CHD9; SPEN; NR2F1; ELF4; BATF3; ZNF117; TFCP2; PSPC1; PCGF1; ZBTB7A; SRCAP; MYCL; BATF; MNDA; HDAC4; CCNC; STAT1; ASCL1; HOXA7; ID2; FOXG1; SLC2A4RG; IFI16; BCL6; EMX2; CTBP2; HDGF; BAZ1A; SMAD1; TLE1; ZSCAN31; ZEB1; AR; ZBED1; ETS1; ACTL6A; NRIP1; FOXA1; HMGN3; GTF3A; ZNF83; MEOX2; ZFPM2; ZBTB20; CARHSP1; MECOM; PDLIM1; ZKSCAN1; APEX1; NR2F2; ZNF91; MEIS2; PPARG; ID4; JUP; FOS